Evidence map›Paper›PMID 28955746›Full record

ArticleBiochemistry and biophysics reports2017

Scaffold-free 3D bio-printed human liver tissue stably maintains metabolic functions useful for drug discovery.

Hideki Kizawa, Eri Nagao, Mitsuru Shimamura, Guangyuan Zhang, Hitoshi Torii

Open access · goldAbstract read
In one paragraph

Article in Biochemistry and biophysics reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 140 citations in OpenAlex.

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  12. Three-Dimensional Spheroids for Cancer Research.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
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  15. Customizable Microfluidic Origami Liver-on-a-Chip (oLOC).Advanced materials technologies · 2022
    Article
  16. Article
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  18. iScience · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hideki KizawaDepartment of Drug Discovery Platform, Cyfuse Biomedical K.K., University of Tokyo, Entrepreneur Plaza, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Eri NagaoDepartment of Drug Discovery Platform, Cyfuse Biomedical K.K., University of Tokyo, Entrepreneur Plaza, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Mitsuru ShimamuraDepartment of Drug Discovery Platform, Cyfuse Biomedical K.K., University of Tokyo, Entrepreneur Plaza, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Guangyuan ZhangDepartment of Drug Discovery Platform, Cyfuse Biomedical K.K., University of Tokyo, Entrepreneur Plaza, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Hitoshi ToriiDepartment of Drug Discovery Platform, Cyfuse Biomedical K.K., University of Tokyo, Entrepreneur Plaza, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
The University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The liver plays a central role in metabolism. Although many studies have described

Indexed as

3D8CPT-cAMP, 8-(4-Chlorophenylthio)adenosine 3′,5′-cyclic monophosphateBio-printingDex, DexamethasoneDrug discoveryECM, Extracellular matrixHE, hematoxylin and eosinLiverMetabolismMRP2, multidrug resistance-associated protein 2MT, Masson's trichromeNAFLD, Non-alcoholic fatty liver diseaseNASH, Non-alcoholic steatohepatitisOAT, organic anion-transportingScaffold-freeTUNEL, TdT-mediated dUTP nick end labeling

Identifiers

PMID28955746
PMCPMC5614670
OpenAlexW2605827552

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.