ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2018
Fracture Risk Assessment in Long-term Care (FRAiL): Development and Validation of a Prediction Model.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Interventions for preventing falls in older people in care facilities.The Cochrane database of systematic reviews · 2025Pooled it
- Predictive value of machine learning on fracture risk in osteoporosis: a systematic review and meta-analysis.BMJ open · 2023Pooled it
- Screening for Osteoporosis in Nonagenarians: A Scoping Review.Journal of the American Geriatrics Society · 2025Article
- Article
- Risk factors and socioeconomic determinants of falls among older adults.Frontiers in public health · 2025Article
- Hip fracture rate and osteoporosis treatment in Ontario: A population-based retrospective cohort study.Archives of osteoporosis · 2024Article
- Prescriber Perspectives and Experiences with Deprescribing Versus Continuing Bisphosphonates in Older Nursing Home Residents with Dementia.Journal of general internal medicine · 2023Article
- Nursing Home PRevention of Injury in DEmentia (NH PRIDE): A pilot study of a remote injury prevention service for NH residents.Journal of the American Geriatrics Society · 2023Article
- The balance of prescriptive and dynamic regulatory policies in nursing homes: Lessons learned from the COVID-19 pandemic.Journal of the American Geriatrics Society · 2023Article
- Perceptions and practices of aged care pharmacists regarding osteoporosis management: a qualitative study.International journal of clinical pharmacy · 2023Article
- Development and validation of the fall-related injury risk in nursing homes (INJURE-NH) prediction tool.Journal of the American Geriatrics Society · 2023Article
- Screening of Fracture Risk and Osteoporosis Among Older Long-term Care Residents: A Prospective Study.The journal of nutrition, health & aging · 2023Article
- Controversies in Osteoporosis Treatment of Nursing Home Residents.Journal of the American Medical Directors Association · 2022Review
- Use of antiretroviral therapy in nursing home residents with HIV.Journal of the American Geriatrics Society · 2022Article
- Skeletal Aging.Mayo Clinic proceedings · 2022Review
- External validation of a new predictive model for falls among inpatients using the official Japanese ADL scale, Bedriddenness ranks: a double-centered prospective cohort study.BMC geriatrics · 2022Article
- Pharmacologic Interventions for Fracture Risk Reduction in the Oldest Old: What Is the Evidence?JBMR plus · 2021Article
- Validation of the Minimum Data Set Items on Falls and Injury in Two Long-Stay Facilities.Journal of the American Geriatrics Society · 2021Article
- Comparative effectiveness of denosumab, teriparatide, and zoledronic acid among frail older adults: a retrospective cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Article
- Are Nursing Home Residents With Dementia Appropriately Treated for Fracture Prevention?Journal of the American Medical Directors Association · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
Background: Strategies used to predict fracture in community-dwellers may not be useful in the nursing home (NH). Our objective was to develop and validate a model (Fracture Risk Assessment in Long-term Care [FRAiL]) to predict the 2-year risk of hip fracture in NH residents using readily available clinical characteristics. Methods: The derivation cohort consisted of 419,668 residents between May 1, 2007 and April 30, 2008 in fee-for service Medicare. Hip fractures were identified using Part A diagnostic codes. Resident characteristics were obtained using the Minimum Data Set and Part D claims. Multivariable competing risk regression was used to model 2-year risk of hip fracture. We validated the model in a remaining 1/3 sample (n = 209,834) and in a separate cohort in 2011 (n = 858,636). Results: Mean age was 84 years (range 65-113 years) and 74.5% were female. During 1.8 years mean follow-up, 14,553 residents (3.5%) experienced a hip fracture. Fifteen characteristics in the final model were associated with an increased risk of hip fracture including dementia severity, ability to transfer and walk independently, prior falls, wandering, and diabetes. In the derivation sample, the concordance index was 0.69 in men and 0.71 in women. Calibration was excellent. Results were similar in the internal and external validation samples. Conclusions: The FRAiL model was developed specifically to identify NH residents at greatest risk for hip fracture, and it identifies a different pattern of risk factors compared with community models. This practical model could be used to screen NH residents for fracture risk and to target intervention strategies.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.