Evidence map›Paper›PMID 28963343›Full record

ArticleThe Biochemical journal2017

Direct visualization of interaction between calmodulin and connexin45.

Juan Zou, Mani Salarian, Yanyi Chen, You Zhuo, Nicole E Brown, John R Hepler, Jenny J Yang

Open access · greenAbstract read
In one paragraph

Article in The Biochemical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. The soluble state of the HIV-1 Vpu protein forms a complex with CaProtein science : a publication of the Protein Society · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. CaInternational journal of molecular sciences · 2023
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Broadening the Mutation Spectrum inFrontiers in medicine · 2021
    Article
  11. Structural Aspects and Prediction of Calmodulin-Binding Proteins.International journal of molecular sciences · 2020
    Review
  12. Review
  13. Article
  14. Review
  15. Design of Calcium-Binding Proteins to Sense Calcium.Molecules (Basel, Switzerland) · 2020
    Review
  16. Calmodulin-Mediated Regulation of Gap Junction Channels.International journal of molecular sciences · 2020
    Review
  17. Article
  18. Article
  19. CaFrontiers in physiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Juan ZouDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, U.S.A.
Mani SalarianDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, U.S.A.
Yanyi ChenDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, U.S.A.
You ZhuoDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, U.S.A.
Nicole E BrownDepartment of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, U.S.A.
John R HeplerDepartment of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, U.S.A.
Jenny J YangDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, U.S.A. jenny@gsu.edu.
Georgia State University · USEmory University · US

Funding

Structure and Function of the G-alpha-i1:RGS14:H-Ras signaling complexR01NS037112 · NINDS · EMORY UNIVERSITY · PI HEPLER, JOHN R · 1998 to 2023
$7.2M
Graduate Training in the Pharmacological StudiesT32GM008602 · NIGMS · EMORY UNIVERSITY · PI HALL, RANDY A. · 1996 to 2021
$5.1M
GAP JUNCTIONS AND IONIC CURRENTS IN DEVELOPING HEARTR01HL042220 · NHLBI · UPSTATE MEDICAL UNIVERSITY · PI VEENSTRA, RICHARD DAVID, YANG, JENNY J. · 1988 to 2013
$3.1M
Regulation of lens connexinsR01EY005684 · NEI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI LOUIS, CHARLES F · 1985 to 2007
$1.7M
Structural Biology of receptor-mediated extracellular calcium signalingR01GM081749 · NIGMS · GEORGIA STATE UNIVERSITY · PI YANG, JENNY J. · 2007 to 2011
$1.2M
Rational Design and Analysis of Calcium Binding ProteinR01GM062999 · NIGMS · GEORGIA STATE UNIVERSITY · PI YANG, JENNY J · 2001 to 2005
$991k
NEI NIH HHS R01 EY005684NHLBI NIH HHS R01 HL042220NIGMS NIH HHS R01 GM062999NIGMS NIH HHS R01 GM081749NIGMS NIH HHS T32 GM008602NINDS NIH HHS R01 NS037112
6 · The paper itself

Abstract

Calmodulin (CaM) is an intracellular Ca

Indexed as

Amino Acid SequenceBinding SitesBioluminescence Resonance Energy Transfer TechniquesCalciumCalmodulinConnexinsEnergy TransferHEK293 CellsHeLa CellsHumansKineticsProtein BindingProtein ConformationSequence HomologySignal TransductionCalciumCalmodulinconnexin 45Connexinscalmodulinconnexin45gap junctionsintracellular calciumprotein–protein interactionsregulation

Identifiers

PMID28963343
PMCPMC5976250
OpenAlexW2758382837

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.