Evidence map›Paper›PMID 28971605›Full record

ArticlePharmacology research & perspectives2017

17β-estradiol reduces Ca

Brent J F Hill, Robin J Dalton, Biny K Joseph, Keshari M Thakali, Nancy J Rusch

Open access · goldAbstract read
In one paragraph

Article in Pharmacology research & perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. The machinery of healthy vasoconstriction: an overview.Pflugers Archiv : European journal of physiology · 2025
    Review
  3. Impact of Estrogen on Purinergic Signaling in Microvascular Disease.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Estrogen regulation of cardiac cAMP-L-type CaCell communication and signaling : CCS · 2019
    Article
  9. Article
  10. 17β-estradiol reduces CaPharmacology research & perspectives · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Brent J F HillDepartment of Biology, University of Central Arkansas Conway, Conway, Arkansas.ORCID 0000-0001-7984-2726
Robin J DaltonDepartment of Biology, University of Central Arkansas Conway, Conway, Arkansas.
Biny K JosephDepartment of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Keshari M ThakaliArkansas Children's Nutrition Center & Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Nancy J RuschDepartment of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
University of Arkansas for Medical Sciences · USUniversity of Central Arkansas · USArkansas Children's Nutrition Center · US

Funding

Understanding Hesitant AdoptersP20GM103429 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Lawrence E Cornett · 2012 to 2026
$60.9M
VIRULENCE MECHANISMS IN ESCHERICHIA COLIP20RR016460 · NCRR · UNIV OF ARKANSAS FOR MED SCIS · PI REYNA, NATHAN · 2001 to 2011
$33.1M
NCRR NIH HHS P20 RR016460NIGMS NIH HHS P20 GM103429
6 · The paper itself

Abstract

One mechanism by which the female sex may protect against elevated coronary vascular tone is inhibition of Ca

Indexed as

AnimalsCalciumCalcium Channels, L-TypeCells, CulturedCoronary VesselsEstradiolEstrogen Receptor alphaEstrogen Receptor betaFemaleGene Expression RegulationMuscle ContractionMyocytes, Smooth MuscleSwineCalciumCalcium Channels, L-TypeEstradiolEstrogen Receptor alphaEstrogen Receptor betacalcium channelcoronary arteryEstrogensexvasodilationα1C subunit

Identifiers

PMID28971605
PMCPMC5625162
OpenAlexW2753324398

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.