Evidence map›Paper›PMID 28976808›Full record

ArticleChannels (Austin, Tex.)2017

Ca

William S Tobelaim, Meidan Dvir, Guy Lebel, Meng Cui, Tal Buki, Asher Peretz, Milit Marom, Yoni Haitin, Diomedes E Logothetis, Joel A Hirsch and 1 more

Open access · goldAbstract read
In one paragraph

Article in Channels (Austin, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Modulation of the IBBA advances · 2023
    Article
  2. Clinically RelevantInternational journal of molecular sciences · 2022
    Article
  3. Modulation of IJournal of cellular physiology · 2022
    Article
  4. Article
  5. Review
  6. Neurohormonal Regulation of IJournal of the American Heart Association · 2020
    Review
  7. A PIPCommunications biology · 2020
    Article
  8. Article
  9. Atomistic Insights of Calmodulin Gating of Complete Ion Channels.International journal of molecular sciences · 2020
    Review
  10. Physical and functional interaction sites in cytoplasmic domains of KCNQ1 and KCNE1 channel subunits.American journal of physiology. Heart and circulatory physiology · 2020
    Article
  11. Review
  12. The Crossroad of Ion Channels and Calmodulin in Disease.International journal of molecular sciences · 2019
    Review
  13. Article
  14. Phosphatidylinositol 4,5-bisphosphate (PIPThe Journal of biological chemistry · 2018
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

William S Tobelaima Department of Physiology & Pharmacology , Sackler Faculty of Medicine and Sagol School of Neurosciences, Tel Aviv University , Tel Aviv , Israel.
Meidan Dvira Department of Physiology & Pharmacology , Sackler Faculty of Medicine and Sagol School of Neurosciences, Tel Aviv University , Tel Aviv , Israel.
Guy Lebelb Department of Biochemistry & Molecular Biology , George S. Wise Faculty of Life Sciences, Institute of Structural Biology, Tel Aviv University , Tel Aviv , Israel.
Meng Cuic Department of Pharmaceutical Sciences , Northeastern University , Boston , MA , USA.
Tal Bukid Laboratory of Structural Physiology, Department of Physiology & Pharmacology , Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv , Israel.
Asher Peretza Department of Physiology & Pharmacology , Sackler Faculty of Medicine and Sagol School of Neurosciences, Tel Aviv University , Tel Aviv , Israel.
Milit Maromd Laboratory of Structural Physiology, Department of Physiology & Pharmacology , Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv , Israel.
Yoni Haitind Laboratory of Structural Physiology, Department of Physiology & Pharmacology , Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv , Israel.
Diomedes E Logothetisc Department of Pharmaceutical Sciences , Northeastern University , Boston , MA , USA.
Joel A Hirschb Department of Biochemistry & Molecular Biology , George S. Wise Faculty of Life Sciences, Institute of Structural Biology, Tel Aviv University , Tel Aviv , Israel.
Bernard Attalia Department of Physiology & Pharmacology , Sackler Faculty of Medicine and Sagol School of Neurosciences, Tel Aviv University , Tel Aviv , Israel.
Tel Aviv University · ILNortheastern University · US

Funding

Structural Determinants of PIP2 RegulationR01HL059949 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Leigh Daniel Plant · 1998 to 2026
$11.6M
NHLBI NIH HHS R01 HL059949
6 · The paper itself

Abstract

In the heart, co-assembly of Kv7.1 with KCNE1 produces the slow I

Indexed as

AnimalsCalciumCalmodulinCells, CulturedCHO CellsCricetulusHumansKCNQ1 Potassium ChannelPhosphatidylinositol 4,5-DiphosphateCalciumCalmodulinKCNQ1 Potassium ChannelKCNQ1 protein, humanPhosphatidylinositol 4,5-DiphosphatecalmodulinKCNQKv7PIP2Potassium channel

Identifiers

PMID28976808
PMCPMC5786183
OpenAlexW2763402483

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.