ArticleCell reports2017
Precocious Interleukin 21 Expression in Naive Mice Identifies a Natural Helper Cell Population in Autoimmune Disease.
Article in Cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 21 citations in OpenAlex.
- Article
- Thymflammation: The Role of a Constitutively Active Inflammatory Network and "Ectopic" Cell Types in the Thymus in the Induction of T Cell Tolerance and Beyond.Immunological reviews · 2025Review
- Investigation of high-mobility group box 1 variants with lymph node status and colorectal cancer risk.World journal of gastrointestinal oncology · 2025Article
- CD4 T Cell-Derived IL-21 Is Critical for Sustaining Plasmodium Infection-Induced Germinal Center Responses and Promoting the Selection of Memory B Cells with Recall Potential.Journal of immunology (Baltimore, Md. : 1950) · 2024Article
- Article
- Stepwise differentiation of follicular helper T cells reveals distinct developmental and functional states.Nature communications · 2023Article
- Type III interferon drives thymic B cell activation and regulatory T cell generation.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- IL-21 is required for the maintenance and pathogenesis of murine Vγ4Frontiers in immunology · 2023Article
- Mitochondrial regulation of acute extrafollicular B-cell responses to COVID-19 severity.Clinical and translational medicine · 2022Article
- Translational regulation of TFH cell differentiation and autoimmune pathogenesis.Science advances · 2022Article
- Tissue-resident CD4Science immunology · 2021Article
- IL-21 in Homeostasis of Resident Memory and Exhausted CD8 T Cells during Persistent Infection.International journal of molecular sciences · 2020Review
- IL-21 from high-affinity CD4 T cells drives differentiation of brain-resident CD8 T cells during persistent viral infection.Science immunology · 2020Article
- Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4Immunity · 2020Article
- Investigation of multi-trait associations using pathway-based analysis of GWAS summary statistics.BMC genomics · 2019Article
- Integration of T-cell receptor, Notch and cytokine signals programs mouse γδ T-cell effector differentiation.Immunology and cell biology · 2018Article
- Relative Contributions of B Cells and Dendritic Cells from Lupus-Prone Mice to CD4Journal of immunology (Baltimore, Md. : 1950) · 2018Article
- Induction of Hypergammaglobulinemia and Autoantibodies byFrontiers in immunology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
Interleukin 21 (IL-21) plays key roles in humoral immunity and autoimmune diseases. It is known to function in mature CD4
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.