ArticleAmerican journal of epidemiology2018
The Relationship Between Occupational Standing and Sitting and Incident Heart Disease Over a 12-Year Period in Ontario, Canada.
Article in American journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 106 citations in OpenAlex.
- Exploring the 'fit for work' principle: The association between occupational physical activity, cardio-respiratory fitness, and mortality - a meta-analysis of male worker data.Scandinavian journal of work, environment & health · 2025Pooled it
- The effect of leisure time physical activity and sedentary behaviour on the health of workers with different occupational physical activity demands: a systematic review.The international journal of behavioral nutrition and physical activity · 2021Pooled it
- Ukumela impilo randomised trial: preliminary findings of height-adjustable sit-to-stand workstations on health outcomes of South African office workers.BMC research notes · 2023Trial
- Standing up against office sitting: A study protocol.The South African journal of physiotherapy · 2020Trial
- The Effects of Occupational and Leisure Time Physical Activity on Health-Related Quality of Life: A Repeated-Measures Longitudinal Study.Sports medicine (Auckland, N.Z.) · 2026Article
- The physical activity health paradox: what is it, why might it happen, and where to go from here?The international journal of behavioral nutrition and physical activity · 2026Review
- Greater amount of lying and reclining associate with cardiovascular disease risk score and several risk factors, while short sitting bouts and standing have opposite relation.American journal of preventive cardiology · 2025Article
- Is Sitting Really the New Smoking? Health of North American Workers Exposed to Prolonged Static Standing.New solutions : a journal of environmental and occupational health policy : NS · 2025Article
- Recovery pulse rate and cardiovascular function indices in young female adults following orthostasis.Journal of biological methods · 2025Article
- Sitting time at work and cardiovascular disease risk-a longitudinal analysis of the Study on Mental Health at Work (S-MGA).International archives of occupational and environmental health · 2025Article
- Standing in the shadows: is standing a tonic or a toxin for cardiometabolic health?British journal of sports medicine · 2024Article
- Device-measured stationary behaviour and cardiovascular and orthostatic circulatory disease incidence.International journal of epidemiology · 2024Article
- The relationship between physical and psychosocial workplace exposures and life expectancy free of musculoskeletal and cardiovascular disease in working life - an analysis based on German health insurance data.BMC public health · 2024Article
- A tree-based corpus annotated with Cyber-Syndrome, symptoms, and acupoints.Scientific data · 2024Article
- Changes in Baropodometric Evaluation and Discomfort during the Workday in Assembly-Line Workers.Healthcare (Basel, Switzerland) · 2024Article
- Revisiting the physical activity paradox: the role of cardiorespiratory fitness in workers with high aerobic demands.Scandinavian journal of public health · 2024Article
- Relationship between cumulative exposure to occupational lifting throughout working life and risk of ischemic heart disease in men and women. The Copenhagen Aging and Midlife Biobank.Annals of work exposures and health · 2024Article
- The 24-h activity cycle and cardiovascular outcomes: establishing biological plausibility using arterial stiffness as an intermediate outcome.American journal of physiology. Heart and circulatory physiology · 2023Review
- Association between biomarkers of redox status and cytokines with different patterns of habitual physical activity in eutrophic and overweight/obese preschoolers: multivariate analysis of a cross-sectional study.BMC public health · 2023Article
- Trajectories of occupational physical activity and risk of later-life mild cognitive impairment and dementia: the HUNT4 70+ study.The Lancet regional health. Europe · 2023Article
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Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
Abstract
While a growing body of research is examining the impacts of prolonged occupational sitting on cardiovascular and other health risk factors, relatively little work has examined the effects of occupational standing. The objectives of this paper were to examine the relationship between occupations that require predominantly sitting and those that require predominantly standing and incident heart disease. A prospective cohort study combining responses to a population health survey with administrative health-care records, linked at the individual level, was conducted in Ontario, Canada. The sample included 7,320 employed labor-market participants (50% male) working 15 hours a week or more and free of heart disease at baseline. Incident heart disease was assessed using administrative records over an approximately 12-year follow-up period (2003-2015). Models adjusted for a wide range of potential confounding factors. Occupations involving predominantly standing were associated with an approximately 2-fold risk of heart disease compared with occupations involving predominantly sitting. This association was robust to adjustment for other health, sociodemographic, and work variables. Cardiovascular risk associated with occupations that involve combinations of sitting, standing, and walking differed for men and women, with these occupations associated with lower cardiovascular risk estimates among men but elevated risk estimates among women.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.