Trial reportStroke2017
Added Value of Vessel Wall Magnetic Resonance Imaging for Differentiation of Nonocclusive Intracranial Vasculopathies.
Trial report in Stroke, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Vessel wall MR imaging of central nervous system vasculitis: a systematic review.Neuroradiology · 2022Pooled it
- MR Intracranial Vessel Wall Imaging: A Systematic Review.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2020Pooled it
- Trial
- Primary angiitis of the central nervous system: predictors of stroke during immunosuppressant treatment.Insights into imaging · 2026Article
- Review
- Voxel-Wise Quantification and Multi-planar Visualization of Plaque Contrast Enhancement in Intracranial Vessel Wall MRI.medRxiv : the preprint server for health sciences · 2025Article
- Intracranial vessel wall lesions on MRI: anatomical and pathological issues.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Review
- Intracranial vessel wall lesions on MRI: anatomical and pathological issues.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Review
- Review
- Association between vertebrobasilar artery calcification and artery-to-artery embolism in the posterior circulation.Scientific reports · 2025Article
- COVID-19 Cerebral Vasculitis With Extensive Involvement of Anterior Circulation and Sparing of Posterior Circulation.Cureus · 2025Article
- Beyond the "string of beads": case-based exploration of diagnostic pitfalls and solutions in reversible cerebral vasoconstriction syndrome.The journal of headache and pain · 2025Review
- Clinical impact and safety of brain biopsy in unexplained central nervous system disorders: a real-world cohort study.Annals of clinical and translational neurology · 2025Article
- High-Resolution Vessel Wall Images and Neuropsychiatric Lupus: A Scoping Review.Diagnostics (Basel, Switzerland) · 2025Review
- DANTE-CAIPI Accelerated Contrast-Enhanced 3D T1: Deep Learning-Based Image Quality Improvement for Vessel Wall MRI.AJNR. American journal of neuroradiology · 2025Article
- Role of Vessel Wall Magnetic Resonance Imaging in the Diagnosis of Intracranial Vasculopathies.Cureus · 2024Article
- Temporal evolution of primary angiitis of the central nervous system (PACNS) on MRI following immunosuppressant treatment.Insights into imaging · 2024Article
- Multimodal imaging approach for the diagnosis of intracranial atherosclerotic disease (ICAD): Basic principles, current and future perspectives.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024Review
- Emerging Concept of Intracranial Arterial Diseases: The Role of High Resolution Vessel Wall MRI.Journal of stroke · 2024Review
- Juvenile dermatomyositis with central nervous system involvement: two case reports from a retrospective single-center cohort, with literature review.Frontiers in pediatrics · 2024Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
background and purposeOur goal is to determine the added value of intracranial vessel wall magnetic resonance imaging (IVWI) in differentiating nonocclusive vasculopathies compared with luminal imaging alone.
methodsWe retrospectively reviewed images from patients with both luminal and IVWI to identify cases with clinically defined intracranial vasculopathies: atherosclerosis (intracranial atherosclerotic disease), reversible cerebral vasoconstriction syndrome, and inflammatory vasculopathy. Two neuroradiologists blinded to clinical data reviewed the luminal imaging of defined luminal stenoses/irregularities and evaluated the pattern of involvement to make a presumed diagnosis with diagnostic confidence. Six weeks later, the 2 raters rereviewed the luminal imaging in addition to IVWI for the pattern of wall involvement, presence and pattern of postcontrast enhancement, and presumed diagnosis and confidence. Analysis was performed on per-lesion and per-patient bases.
resultsThirty intracranial atherosclerotic disease, 12 inflammatory vasculopathies, and 12 reversible cerebral vasoconstriction syndrome patients with 201 lesions (90 intracranial atherosclerotic disease, 64 reversible cerebral vasoconstriction syndrome, and 47 inflammatory vasculopathy lesions) were included. For both per-lesion and per-patient analyses, there was significant diagnostic accuracy improvement with luminal imaging+IVWI when compared with luminal imaging alone (per-lesion: 88.8% versus 36.1%;
conclusionsIVWI can significantly improve the differentiation of nonocclusive intracranial vasculopathies when combined with traditional luminal imaging modalities.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.