ArticleFrontiers in aging neuroscience2017
Exercise Training Increases Parietal Lobe Cerebral Blood Flow in Chronic Stroke: An Observational Study.
Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Impact of enhanced external counterpulsation treatment on cerebral blood flow and functional outcomes in ischemic stroke patients: a systematic review and meta-analysis.QJM : monthly journal of the Association of Physicians · 2026Pooled it
- Effects of 16 Weeks of Taekwondo Training on the Cerebral Blood Flow Velocity, Circulating Neurotransmitters, and Subjective Well-Being of Obese Postmenopausal Women.International journal of environmental research and public health · 2021Trial
- Effects of Different Intervention Time Points of Early Rehabilitation on Patients with Acute Ischemic Stroke: A Single-Center, Randomized Control Study.BioMed research international · 2021Trial
- Changes in Moderate Intensity Physical Activity Are Associated With Better Cognition in the Multilevel Intervention for Physical Activity in Retirement Communities (MIPARC) Study.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2019Trial
- Article
- Associations of cardiorespiratory fitness with cerebral cortical thickness and gray matter volume across the adult lifespan.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- Article
- Use of cortical hemodynamic responses in digital therapeutics for upper limb rehabilitation in patients with stroke.Journal of neuroengineering and rehabilitation · 2024Article
- Influence of sex and presence of cardiovascular risk factors on relations between cardiorespiratory fitness and cerebrovascular hemodynamics.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Regional cortical perfusion increases induced by a 6-month endurance training in young sedentary adults.Frontiers in aging neuroscience · 2022Article
- Exercise-Based Stroke Rehabilitation: Clinical Considerations Following the COVID-19 Pandemic.Neurorehabilitation and neural repair · 2022Article
- Associations Between Time After Stroke and Exercise Training Outcomes: A Meta-Regression Analysis.Journal of the American Heart Association · 2021Article
- Inflammation-relevant microbiome signature of the stroke brain, gut, spleen, and thymus and the impact of exercise.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation.Physiological reviews · 2021Review
- A Short Bout of Exercise Prior to Stroke Improves Functional Outcomes by Enhancing Angiogenesis.Neuromolecular medicine · 2019Article
- Dose-dependent association of accelerometer-measured physical activity and sedentary time with brain perfusion in aging.Experimental gerontology · 2019Article
- The Protective Role of Regular Aerobic Exercise on Vascular Function with Aging.Current opinion in physiology · 2019Article
- Neuroprotective potential of exercise preconditioning in stroke.Conditioning medicine · 2017Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exercise is increasingly recommended as an essential component of stroke rehabilitation, yet uncertainty remains with respect to its direct effect on the cerebral vasculature. The current study first demonstrated the repeatability of pseudo-continuous arterial spin labeling (ASL) magnetic resonance imaging (MRI) in older adults with stroke, and then investigated the change in cerebrovascular function following a 6-month cardiovascular rehabilitation program. In the repeatability study, 12 participants at least 3 months post-stroke underwent two ASL imaging scans 1 month apart. In the prospective observational study, eight individuals underwent ASL imaging and aerobic fitness testing before and after a 6-month cardiovascular rehabilitation program. Cerebral blood flow (CBF) and the spatial coefficient of variation of CBF (sCoV) were quantified to characterize tissue-level perfusion and large cerebral artery transit time properties, respectively. In repeat scanning, intraclass correlation (ICC) indicated moderate test-retest reliability for global gray matter CBF (ICC = 0.73) and excellent reliability for sCoV (ICC = 0.94). In the observational study, gray matter CBF increased after training (baseline: 40 ± 13 vs. 6-month: 46 ± 12 ml·100 g
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.