Evidence map›Paper›PMID 29046297›Full record

ArticleAmerican journal of physiology. Renal physiology2018

Renal and colonic potassium transporters in the pregnant rat.

Crystal A West, Paul A Welling, David A West, Richard A Coleman, Kit-Yan Cheng, Chao Chen, Thomas D DuBose, Jill W Verlander, Chris Baylis, Michelle L Gumz

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Renal KFrontiers in physiology · 2023
    Review
  7. Article
  8. Article
  9. Potassium homeostasis: sensors, mediators, and targets.Pflugers Archiv : European journal of physiology · 2022
    Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Crystal A WestDepartment of Medicine, Georgetown University, Washington, District of Columiba.
Paul A WellingDepartment of Physiology, University of Maryland School of Medicine , Baltimore, Maryland.
David A WestDepartment of Medicine, Georgetown University, Washington, District of Columiba.
Richard A ColemanDepartment of Physiology, University of Maryland School of Medicine , Baltimore, Maryland.
Kit-Yan ChengDepartment of Medicine, University of Florida , Gainesville, Florida.
Chao ChenDepartment of Medicine, University of Florida , Gainesville, Florida.
Thomas D DuBoseDepartment of Medicine, Wake Forest School of Medicine , Winston-Salem, North Carolina.
Jill W VerlanderDepartment of Medicine, University of Florida , Gainesville, Florida.ORCID 0000-0002-4096-4897
Chris BaylisDepartment of Medicine, University of Florida , Gainesville, Florida.
Michelle L GumzDepartment of Medicine, University of Florida , Gainesville, Florida.
University of Florida · USGeorgetown University · USUniversity of Maryland, Baltimore · USWake Forest University · US

Funding

WNK-SPAK signaling in the Distal NephronR01DK093501 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric J Delpire, Paul A Welling · 2012 to 2026
$12.1M
Molecular of ROMK Channel FunctionR01DK054231 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI Paul A Welling · 1998 to 2026
$7.7M
Polarized Trafficking of K+ Channels in the KidneyR01DK063049 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI WELLING, PAUL A · 2003 to 2016
$4.7M
Nitrix Oxide in Chronic Renal DiseaseR01DK056843 · NIDDK · WEST VIRGINIA UNIVERSITY · PI BAYLIS, CHRISTINE · 2001 to 2015
$3.4M
Multidisciplinary Training Program in HypertensionT32HL083810 · NHLBI · UNIVERSITY OF FLORIDA · PI WOOD, CHARLES E · 2007 to 2017
$2.5M
Per1 and the kidney clock in hypertensionR01DK109570 · NIDDK · UNIVERSITY OF FLORIDA · PI GUMZ, MICHELLE L · 2017 to 2021
$1.5M
IMCD phosphodiesterase in pregnancy;role in ECFVER01HD041571 · NICHD · UNIVERSITY OF FLORIDA · PI BAYLIS, CHRISTINE · 2004 to 2008
$1.3M
A Functional Role for the Circadian Clock Protein Per1 in the Regulation of ??ENaK01DK085193 · NIDDK · UNIVERSITY OF FLORIDA · PI GUMZ, MICHELLE L · 2010 to 2014
$625k
NHLBI NIH HHS T32 HL083810NICHD NIH HHS R01 HD041571NIDDK NIH HHS K01 DK085193NIDDK NIH HHS R01 DK054231NIDDK NIH HHS R01 DK056843NIDDK NIH HHS R01 DK063049NIDDK NIH HHS R01 DK093501NIDDK NIH HHS R01 DK109570
6 · The paper itself

Abstract

Gestational potassium retention, most of which occurs during late pregnancy, is essential for fetal development. The purpose of this study was to examine mechanisms underlying changes in potassium handling by the kidney and colon in pregnancy. We found that potassium intake and renal excretion increased in late pregnancy while fecal potassium excretion remained unchanged and that pregnant rats exhibited net potassium retention. By quantitative PCR we found markedly increased H

Indexed as

AnimalsBiological TransportColonFemaleGestational AgeH(+)-K(+)-Exchanging ATPaseIntestinal ReabsorptionKidney Tubules, CollectingLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsPotassiumPotassium Channels, Inwardly RectifyingPregnancyRats, Sprague-DawleyRenal EliminationRenal ReabsorptionH(+)-K(+)-Exchanging ATPaseKcnj1 protein, ratLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsPotassiumPotassium Channels, Inwardly Rectifyingbig potassium channelBKHKA2H+-K+-ATPase type 2renal outer medullary potassium channelROMK

Identifiers

PMID29046297
PMCPMC5866449
OpenAlexW2765815660

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.