Evidence map›Paper›PMID 29064009›Full record

ArticleEuropean journal of epidemiology2017

The Rotterdam Study: 2018 update on objectives, design and main results.

M Arfan Ikram, Guy G O Brusselle, Sarwa Darwish Murad, Cornelia M van Duijn, Oscar H Franco, André Goedegebure, Caroline C W Klaver, Tamar E C Nijsten, Robin P Peeters, Bruno H Stricker and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in European journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07207603 (Observational Cohort Pilot Study on Cardiovascular Prevention in Citizens Living in Milano-Bicocca District), which is not on this map. Cited by 234 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
234citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07207603 enrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Observational Cohort Pilot Study on Cardiovascular Prevention in Citizens Living in Milano-Bicocca District

TypeobservationalSponsorUniversity of Milano BicoccaRan2024 to 2025Enrolled1,000ConditionsCardiovascular Risk Factors (e.g., Hypertension)ArmsNo intervention
3 · Its place in the literature

Who cites it

234 citing papers in PubMed, 12 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Update of the fracture risk prediction tool FRAX: a systematic review of potential cohorts and analysis plan.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
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  13. Article
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  16. Observational
  17. Article
  18. Objective physical activity and Alzheimer's disease burden in the population-based Rotterdam Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  19. Article
  20. Article

174 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

M Arfan IkramDepartment of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands. m.a.ikram@erasmusmc.nl.
Guy G O BrusselleDepartment of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Sarwa Darwish MuradDepartment of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
Cornelia M van DuijnDepartment of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Oscar H FrancoDepartment of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
André GoedegebureDepartment of Otolaryngology, Erasmus Medical Center, Rotterdam, The Netherlands.
Caroline C W KlaverDepartment of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Tamar E C NijstenDepartment of Dermatology, Erasmus Medical Center, Rotterdam, The Netherlands.
Robin P PeetersDepartment of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Bruno H StrickerDepartment of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Henning TiemeierDepartment of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
André G UitterlindenDepartment of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Meike W VernooijDepartment of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Albert HofmanDepartment of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric, dermatological, otolaryngological, locomotor, and respiratory diseases. As of 2008, 14,926 subjects aged 45 years or over comprise the Rotterdam Study cohort. Since 2016, the cohort is being expanded by persons aged 40 years and over. The findings of the Rotterdam Study have been presented in over 1500 research articles and reports (see www.erasmus-epidemiology.nl/rotterdamstudy ). This article gives the rationale of the study and its design. It also presents a summary of the major findings and an update of the objectives and methods.

Indexed as

Epidemiologic Research DesignAgedAged, 80 and overChronic DiseaseFemaleHumansLife ExpectancyMaleMiddle AgedNetherlandsPopulation SurveillanceProspective StudiesRisk FactorsBiomarkersCardiovascular diseasesCohort studyDermatological diseasesEndocrine diseasesEpidemiologic methodsGenetic epidemiologyLiver diseasesNeurological diseasesOncologyOphthalmic diseasesOtolaryngological diseasesPharmacoepidemiologyPsychiatric diseasesRenal diseasesRespiratory diseases

Identifiers

PMID29064009
PMCPMC5662692

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.