Evidence map›Paper›PMID 29065451›Full record

ArticleMolecules (Basel, Switzerland)2017

Inhibitory Effects of Siegesbeckia orientalis Extracts on Advanced Glycation End Product Formation and Key Enzymes Related to Metabolic Syndrome.

Wei-Chin Hung, Xue-Hua Ling, Chi-Chang Chang, Hsia-Fen Hsu, Shih-Wei Wang, Yi-Chen Lee, Ci Luo, Yun-Tzu Lee, Jer-Yiing Houng

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

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  5. Protective Mechanism of Leucine and Isoleucine against HOxidative medicine and cellular longevity · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Wei-Chin HungDivision of Cardiology, E-Da Hospital, Kaohsiung 82445, Taiwan. ed102600@edah.org.tw.
Xue-Hua LingGraduate Institute of Biotechnology and Chemical Engineering, I-Shou University, Kaohsiung 84001, Taiwan. ed107312@gmail.com.
Chi-Chang ChangDepartment of Obstetrics & Gynecology, E-Da Hospital/I-Shou University, Kaohsiung 82445, Taiwan. ed101779@edah.org.tw.
Hsia-Fen HsuDepartment of Nutrition, I-Shou University, Kaohsiung 82445, Taiwan. fen153848@gmail.com.
Shih-Wei WangDivision of Allergy, Immunology, and Rheumatology, Department of Internal Medicine, E-Da Hospital/I-Shou University, Kaohsiung 82445, Taiwan. shihwei8888@gmail.com.
Yi-Chen LeeDepartment of Nutrition Therapy, E-Da Hospital, Kaohsiung 82445, Taiwan. ed103549@edah.org.tw.
Ci LuoDepartment of Nutrition, I-Shou University, Kaohsiung 82445, Taiwan. r9620239@yahoo.com.tw.
Yun-Tzu LeeDepartment of Nutrition, I-Shou University, Kaohsiung 82445, Taiwan. lisa10143018@gmail.com.
Jer-Yiing HoungGraduate Institute of Biotechnology and Chemical Engineering, I-Shou University, Kaohsiung 84001, Taiwan. jyhoung@isu.edu.tw.ORCID 0000-0002-9723-9987
E-Da Hospital · TWI-Shou University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic syndrome typically includes Type 2 diabetes associated with hyperglycemia, central obesity, dyslipidemia and hypertension. It is highly related to oxidative stress, formation of advanced glycated end products (AGEs) and key enzymes, such as carbohydrate digesting enzymes like pancreatic α-amylase and intestinal α-glucosidase, pancreatic lipase and angiotensin I-converting enzyme (ACE). This study used an in vitro approach to assess the potential of four extracts of

Indexed as

alpha-GlucosidasesAngiotensin-Converting Enzyme InhibitorsAntioxidantsAsteraceaeFlavonoidsGlycation End Products, AdvancedGlycoside Hydrolase InhibitorsHumansHyperglycemiaLipaseMetabolic SyndromeOxidative StressPancreatic alpha-AmylasesPlant Extractsalpha-GlucosidasesAngiotensin-Converting Enzyme InhibitorsAntioxidantsFlavonoidsGlycation End Products, AdvancedGlycoside Hydrolase InhibitorsLipasePancreatic alpha-AmylasesPlant Extractsadvanced glycation end productsangiotensin I-converting enzymeantioxidationlipaseSiegesbeckia orientalis linneα-amylaseα-glucosidase

Identifiers

PMID29065451
PMCPMC6151556
OpenAlexW2766878053

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.