ArticleGenetics2017
Polygenicity and Epistasis Underlie Fitness-Proximal Traits in the
Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed.
- Additive effects of environmental and demographic variation shape the repeatability of evolution across replicated experiments.Evolution letters · 2026Article
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- Discovery and characterization of gene-by-environment and epistatic genetic effects in a vertebrate model.Cell genomics · 2026Article
- Natural variation suggests candidate genes underlying Caenorhabditis elegans susceptibility to diverse toxicants.Toxicological sciences : an official journal of the Society of Toxicology · 2026Article
- Article
- Natural variation suggests candidate genes underlyingbioRxiv : the preprint server for biology · 2025Article
- The regulatory architecture of gene expression variation in Caenorhabditis elegans revealed by multi-strain allele-specific analysis.Genetics · 2025Article
- Article
- Phenotypic tolerance for rDNA copy number variation within the natural range of C. elegans.PLoS genetics · 2025Article
- The regulatory architecture of gene expression variation inbioRxiv : the preprint server for biology · 2025Article
- Selection Can Favor a Recombination Landscape That Limits Polygenic Adaptation.Molecular biology and evolution · 2025Article
- Life history in Caenorhabditis elegans: from molecular genetics to evolutionary ecology.Genetics · 2024Review
- Host defense alteration in Caenorhabditis elegans after evolution under ionizing radiation.BMC ecology and evolution · 2024Article
- Natural variation in infection specificity of Caenorhabditis briggsae isolates by two RNA viruses.PLoS pathogens · 2024Article
- Environmental radiation exposure at Chornobyl has not systematically affected the genomes or chemical mutagen tolerance phenotypes of local worms.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Heritable epigenetic variation facilitates long-term maintenance of epigenetic and genetic variation.G3 (Bethesda, Md.) · 2024Article
- Genome-wide association and environmental suppression of the mortal germline phenotype of wild C. elegans.EMBO reports · 2023Article
- Microbes are potential key players in the evolution of life histories and aging inEcology and evolution · 2023Article
- Article
- Embracing Complexity: Yeast Evolution Experiments Featuring Standing Genetic Variation.Journal of molecular evolution · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Understanding the genetic basis of complex traits remains a major challenge in biology. Polygenicity, phenotypic plasticity, and epistasis contribute to phenotypic variance in ways that are rarely clear. This uncertainty can be problematic for estimating heritability, for predicting individual phenotypes from genomic data, and for parameterizing models of phenotypic evolution. Here, we report an advanced recombinant inbred line (RIL) quantitative trait locus mapping panel for the hermaphroditic nematode
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.