Evidence mapPaperPMID 29066847Full record

ArticleScientific reports2017

Passive and Active Triaxial Wall Mechanics in a Two-Layer Model of Porcine Coronary Artery.

Yuan Lu, Hao Wu, Jiahang Li, Yanjun Gong, Jiahui Ma, Ghassan S Kassab, Yong Huo, Wenchang Tan, Yunlong Huo

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. [Experimental measurement and modeling analysis of active and passive mechanical properties of arterial vessel wall].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Yuan LuDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Hao WuDepartment of Mechanics and Engineering Science, College of Engineering, Peking University, Beijing, China.
Jiahang LiDepartment of Mechanics and Engineering Science, College of Engineering, Peking University, Beijing, China.
Yanjun GongDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Jiahui MaSchool of Public Health, Peking University, Beijing, China.
Ghassan S KassabCalifornia Medical Innovations Institute, San Diego, USA.
Yong HuoDepartment of Cardiology, Peking University First Hospital, Beijing, China. huoyong@263.net.cn.
Wenchang TanDepartment of Mechanics and Engineering Science, College of Engineering, Peking University, Beijing, China. tanwch@pku.edu.cn.
Yunlong HuoDepartment of Mechanics and Engineering Science, College of Engineering, Peking University, Beijing, China. yhuo@pku.edu.cn.ORCID 0000-0003-4121-3224
Peking University · CNCalifornia Medical Innovations Institute · USHong Kong University of Science and Technology · HK

Funding

NHLBI NIH HHS R01 HL117990
6 · The paper itself

Abstract

Triaxial active and passive mechanical properties of coronary arteries are needed for understanding arterial mechanics in health and disease. The aim of the study was to quantify both active and passive strain energy functions in circumferential, axial and radial directions based on the experimental measurement. Moreover, a two-layer computational model was used to determine the transmural distribution of stresses and strains across the vessel wall. The first Piola-Kirchhoff stresses in the three normal directions had the approximate relationship as:[Formula: see text]. The two-layer model showed that circumferential Cauchy stresses increased significantly from the intima layer to the interface between media and adventitia layers (from ~80 to 160 kPa), dropped abruptly at the interface (from ~160 to <5 kPa), and increased slightly towards the outer boundary of the adventitia layer. In contrast, absolute values of radial Cauchy stress decreased continuously from the inner to outer boundaries of the vessel wall (from ~11 kPa to zero). Smooth muscle cell contraction significantly increased the ratio of radial to circumferential Cauchy stresses at the intima-media layer, which had the highest values at the intima layer.

Indexed as

Coronary VesselsMechanical PhenomenaModels, BiologicalAnimalsBiomechanical PhenomenaStress, MechanicalSwine

Identifiers

PMID29066847
PMCPMC5655692
OpenAlexW2766600635

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.