Evidence map›Paper›PMID 29071066›Full record

ReviewF1000Research2017

The emerging role of PET imaging in dementia.

Leonardo Iaccarino, Arianna Sala, Silvia Paola Caminiti, Daniela Perani

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Clozapine induces astrocyte-dependent FDG-PET hypometabolism.European journal of nuclear medicine and molecular imaging · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. CSF p-tau/AβEuropean journal of nuclear medicine and molecular imaging · 2020
    Article
  13. Review
  14. Review
  15. Brain metabolic signatures across the Alzheimer's disease spectrum.European journal of nuclear medicine and molecular imaging · 2020
    Article
  16. Article
  17. Automated synthesis of [EJNMMI radiopharmacy and chemistry · 2019
    Article
  18. Heterogeneous brain FDG-PET metabolic patterns in patients with C9orf72 mutation.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Leonardo IaccarinoVita-Salute San Raffaele University, Milan, Italy.
Arianna SalaVita-Salute San Raffaele University, Milan, Italy.
Silvia Paola CaminitiVita-Salute San Raffaele University, Milan, Italy.
Daniela PeraniVita-Salute San Raffaele University, Milan, Italy.ORCID https://orcid.org/0000-0002-9784-292X
Vita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A compelling need in the field of neurodegenerative diseases is the development and validation of biomarkers for early identification and differential diagnosis. The availability of positron emission tomography (PET) neuroimaging tools for the assessment of molecular biology and neuropathology has opened new venues in the diagnostic design and the conduction of new clinical trials. PET techniques, allowing the in vivo assessment of brain function and pathology changes, are increasingly showing great potential in supporting clinical diagnosis also in the early and even preclinical phases of dementia. This review will summarize the most recent evidence on fluorine-18 fluorodeoxyglucose-, amyloid -, tau -, and neuroinflammation - PET tools, highlighting strengths and limitations and possible new perspectives in research and clinical applications. Appropriate use of PET tools is crucial for a prompt diagnosis and target evaluation of new developed drugs aimed at slowing or preventing dementia.

Indexed as

amyloidbiomarkerdementiadiagnosisfluorodeoxyglucosemolecular imagingneuroinflammationPETprognosistau

Identifiers

PMID29071066
PMCPMC5639932
OpenAlexW2762309236

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.