Evidence map›Paper›PMID 29071192›Full record

ArticleNanotheranostics2017

The biocompatibility studies of polymer dots on pregnant mice and fetuses.

Na Wu, Zheng Zhang, Jie Zhou, Zezhou Sun, Yueyue Deng, Guimiao Lin, Ming Ying, Xiaomei Wang, Ken-Tye Yong, Changfeng Wu and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanotheranostics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Na WuKey laboratory of Optoelectronic Devices and System of The Ministry of Education/Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen Guangdong Province 518060, China.
Zheng ZhangKey laboratory of Optoelectronic Devices and System of The Ministry of Education/Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen Guangdong Province 518060, China.
Jie ZhouKey laboratory of Optoelectronic Devices and System of The Ministry of Education/Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen Guangdong Province 518060, China.
Zezhou SunState key laboratory on integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University Changchun, Jinlin 130012, China.
Yueyue DengKey laboratory of Optoelectronic Devices and System of The Ministry of Education/Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen Guangdong Province 518060, China.
Guimiao LinKey laboratory of Biomedical Engineering of Shenzhen, College of medicine, Shenzhen University, Shenzhen, Guangdong 518060, China.
Ming YingShenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science, Shenzhen Key Laboratory of Microbia Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China.
Xiaomei WangKey laboratory of Biomedical Engineering of Shenzhen, College of medicine, Shenzhen University, Shenzhen, Guangdong 518060, China.
Ken-Tye YongSchool of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, Singapore.
Changfeng WuDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China.
Gaixia XuKey laboratory of Optoelectronic Devices and System of The Ministry of Education/Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen Guangdong Province 518060, China.
Shenzhen University · CNNanyang Technological University · SGSouthern University of Science and Technology · CNState Key Laboratory on Integrated Optoelectronics · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Semiconducting polymer dots (Pdots) are small nanoparticles consisting primarily of fluorescent pi-conjugated polymers which show superior optical properties for biological imaging and biosensors. It is necessary to explore systematically the toxicity of Pdots on animals before extensive biomedical applications. The reproductive system is very sensitive to the external invasion and essential for species reproduction as well. In this work, we used the pregnant mice to investigate the reproductive toxicity of Pdots. The changes in body weight of each maternal mouse were recorded every two days. The main organs were collected and analyzed as soon as all the pregnant mice were sacrificed on the 15

Indexed as

nanoparticlespolymer dotreproductive toxicity.

Identifiers

PMID29071192
PMCPMC5646735
OpenAlexW2660655242

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.