Evidence map›Paper›PMID 29072164›Full record

Trial reportClinical nutrition ESPEN2017

Effects of a lipid emulsion containing fish oil on polyunsaturated fatty acid profiles, growth and morbidities in extremely premature infants: A randomized controlled trial.

Svetlana Najm, Chatarina Löfqvist, Gunnel Hellgren, Eva Engström, Pia Lundgren, Anna-Lena Hård, Alexandre Lapillonne, Karin Sävman, Anders K Nilsson, Mats X Andersson and 2 more

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical nutrition ESPEN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 5 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 5 syntheses or guidelines pooled it, 135 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. New-generation intravenous fat emulsions and bronchopulmonary dysplasia in preterm infants: a systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2020
    Pooled it
  5. Lipid emulsions for parenterally fed preterm infants.The Cochrane database of systematic reviews · 2019
    Pooled it
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  19. Targeting adenosine APurinergic signalling · 2025
    Review
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Svetlana NajmDepartment of Paediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Chatarina LöfqvistSection for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Electronic address: chatarina.lofqvist@gu.se.
Gunnel HellgrenDepartment of Paediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Section for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Eva EngströmDepartment of Paediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Pia LundgrenSection for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Anna-Lena HårdSection for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Alexandre LapillonneDepartment of Neonatology, Paris Descartes University, APHP Necker Hospital, Paris, France.
Karin SävmanDepartment of Paediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Anders K NilssonSection for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Mats X AnderssonDepartment of Biology and Environmental Sciences, The Faculty of Science, University of Gothenburg, Gothenburg, Sweden.
Lois E H SmithThe Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Ann HellströmSection for Ophthalmology, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
University of Gothenburg · SEBoston Children's Hospital · USDélégation Paris 5 · FR

Funding

SYNAPTIC MECHANISMS IN HIPPOCAMPAL EPILEPTOGENESISP30HD018655 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI WOOLF, CLIFFORD J · 1985 to 2015
$26.2M
Dietary control of angiogenesis in retinopathy modelsR01EY017017 · NEI · BOSTON CHILDREN'S HOSPITAL · PI Zhongjie Fu, Lois Smith · 2006 to 2026
$11.8M
Novel therapies to inhibit Diabetic RetinopathyR24EY024864 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI KERN, TIMOTHY S · 2015 to 2019
$8.1M
Mouse Neurodevelopmental Behavior CoreU54HD090255 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI FAGIOLINI, MICHELA · 2016 to 2020
$5.2M
NEI NIH HHS R01 EY017017NEI NIH HHS R24 EY024864NICHD NIH HHS P30 HD018655NICHD NIH HHS U54 HD090255
6 · The paper itself

Abstract

BACKGROUND &

aimsThe purpose of the study was to compare the effects of the parenteral emulsion SMOFlipid

methodsNinety infants born at gestational age <28 weeks were randomized to treatment with SMOFlipid

resultsInfants on SMOFlipid

conclusionSupplementation with SMOFlipid

Indexed as

Infant, Extremely PrematureBronchopulmonary DysplasiaChild DevelopmentFat Emulsions, IntravenousFatty Acids, UnsaturatedFemaleFish OilsHumansInfant, NewbornMaleParenteral NutritionRetinopathy of PrematurityTreatment OutcomeFat Emulsions, IntravenousFatty Acids, UnsaturatedFish OilsGrowthLong-chain polyunsaturated fatty acidsMorbiditiesParenteral nutritionPreterm

Identifiers

PMID29072164
PMCPMC5784264
OpenAlexW2610403609

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.