ArticleFrontiers in physiology2017
Acute and Chronic Effects of Endurance Running on Inflammatory Markers: A Systematic Review.
Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Acute Inflammatory Responses to Blood Flow Restriction Training: A Systematic Review.Sports medicine - open · 2025Pooled it
- Meta-analysis of the effect of curcumin supplementation on skeletal muscle damage status.PloS one · 2024Pooled it
- Effect of Acute and Chronic Aerobic Exercise on Immunological Markers: A Systematic Review.Frontiers in physiology · 2019Pooled it
- The influence of exercise modality on the inflammatory response to high-intensity interval training.ImmunoHorizons · 2026Trial
- Effects of turmeric extract supplementation on inflammation and muscle damage after a half-marathon race: a randomized, double-blind, placebo-controlled trial.European journal of applied physiology · 2020Trial
- The Relationship Between Biomarkers of Exercise-Induced Gastrointestinal Syndrome and Exercise-Associated Gastrointestinal Symptoms.Sports (Basel, Switzerland) · 2026Article
- Early Cardiac Responses to Half-Marathon Running in Amateur Athletes: Implications for Cardiovascular Health and Safe Exercise Participation.Journal of functional morphology and kinesiology · 2026Article
- Reference Interval Establishment for Neutrophil-To-Lymphocyte Ratio, Platelet-To-Lymphocyte Ratio, and Systemic Immune-Inflammation Index in Athletes: Analysis of Sex and Sport Type Impact.Journal of clinical laboratory analysis · 2025Article
- Changes in the hormonal and inflammatory profile of young sprint- and endurance-trained athletes following a sports camp: a nonrandomized pretest-posttest study.BMC sports science, medicine & rehabilitation · 2024Article
- The Impact of Exercise on Interleukin-6 to Counteract Immunosenescence: Methodological Quality and Overview of Systematic Reviews.Healthcare (Basel, Switzerland) · 2024Review
- Understanding the dynamics of inflammatory mediators in response to mind-body movement therapies (MBMTs): A systematic review and meta-analysis of studies in healthy subjects.Brain behavior and immunity integrative · 2023Article
- The metabolic recovery of marathon runners: an untargetedFrontiers in physiology · 2023Article
- The impact of different forms of exercise on endothelial progenitor cells in healthy populations.European journal of applied physiology · 2022Review
- Recommendations for marathon runners: on the application of recommender systems and machine learning to support recreational marathon runners.User modeling and user-adapted interaction · 2022Article
- Women's Lives Matter-The Critical Need for Women to Prioritize Optimal Physical Activity to Reduce COVID-19 Illness Risk and Severity.International journal of environmental research and public health · 2021Review
- Characterizing Marathon-Induced Metabolic Changes UsingMetabolites · 2021Article
- Recovery-Stress Response of Blood-Based Biomarkers.International journal of environmental research and public health · 2021Article
- Impact of Olive Oil Supplement Intake on Dendritic Cell Maturation after Strenuous Physical Exercise: A Preliminary Study.International journal of environmental research and public health · 2021Article
- Epicardial Adipose Tissue and Cardiovascular Risk Assessment in Ultra-Marathon Runners: A Pilot Study.International journal of environmental research and public health · 2021Article
- Effects of marathon race on selected myokines and sclerostin in middle-aged male amateur runners.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In order to understand the effect of endurance running on inflammation, it is necessary to quantify the extent to which acute and chronic running affects inflammatory mediators. The aim of this study was to summarize the literature on the effects of endurance running on inflammation mediators. Electronic searches were conducted on PubMED and Science Direct with no limits of date and language of publication. Randomized controlled trials (RCTs) and non-randomized controlled trials (NRCTs) investigating the acute and chronic effects of running on inflammation markers in runners were reviewed by two researchers for eligibility. The modified Downs and Black checklist for the assesssments of the methodological quality of studies was subsequently used. Fifty-one studies were finally included. There were no studies with elite athletes. Only two studies were chronic interventions. Results revealed that acute and chronic endurance running may affect anti- and pro-inflammatory markers but methodological differences between studies do not allow comparisons or generalization of the results. The information provided in this systematic review would help practitioners for better designing further studies while providing reference values for a better understanding of inflammatory responses after different running events. Further longitudinal studies are needed to identify the influence of training load parameters on inflammatory markers in runners of different levels and training background.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.