SynthesisWorld journal for pediatric & congenital heart surgery2018
The Perspective of the Intensivist on Inotropes and Postoperative Care Following Pediatric Heart Surgery: An International Survey and Systematic Review of the Literature.
Synthesis in World journal for pediatric & congenital heart surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 49 citations in OpenAlex.
- Trial
- Preoperative Administration of Levosimendan to Prevent Low Cardiac Output Syndrome Following Pediatric Cardiac Surgery: A Retrospective Study.Clinics and practice · 2026Article
- Trends and Challenges in Noninvasive Hemodynamic Monitoring of Neonates Following Cardiac Surgery: A Narrative Review.Life (Basel, Switzerland) · 2025Review
- Risk Factors for low Cardiac Output Syndrome in Children less than 6 years old Undergoing Ventricular Septal Defect Closure: a Retrospective Cohort Study.Pediatric cardiology · 2025Article
- Article
- EVLW by Lung Ultrasound to Predict Short-Term Post Operative Outcomes in Pediatric Cardiac Surgery - A Prospective Observational Study.Annals of cardiac anaesthesia · 2025Observational
- Short term outcomes of the first pediatric cardiac surgery program in Rwanda.Journal of cardiothoracic surgery · 2024Article
- Inotropes for the prevention of low cardiac output syndrome and mortality for paediatric patients undergoing surgery for congenital heart disease: a network meta-analysis.The Cochrane database of systematic reviews · 2024Review
- Cardiac echocardiogram findings of severe acute respiratory syndrome coronavirus-2-associated multi-system inflammatory syndrome in children.Cardiology in the young · 2022Article
- Effect of Intelligent Medical Data Technology in Postoperative Nursing Care.BioMed research international · 2022Article
- Assessment of postoperative risk factors for EEG abnormalities in routine clinical management after paediatric cardiopulmonary bypass.Interactive cardiovascular and thoracic surgery · 2021Article
- Contemporary Trends and Risk Factors of Hemodynamic and Myocardial Mechanics Derived by the Pressure Recording Analytical Method After Pediatric Cardiopulmonary Bypass.Frontiers in cardiovascular medicine · 2021Article
- Stone Paper as a New Substrate to Fabricate Flexible Screen-Printed Electrodes for the Electrochemical Detection of Dopamine.Sensors (Basel, Switzerland) · 2020Article
- Babies and Children at Last: Pediatric Cardiac Output Monitoring in the Twenty-first Century.Anesthesiology · 2019Article
- Vasopressin Is No Inotrope.World journal for pediatric & congenital heart surgery · 2018Article
- Acute left heart failure with pulmonary edema during resection of pediatric neuroblastoma: case report.Brazilian journal of anesthesiology (Elsevier)Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionInotropes are frequently being used in children undergoing heart surgery to prevent or treat low cardiac output syndrome (LCOS). There is only limited evidence that inotropes actually positively influence postoperative outcome. Our aim was to describe the current international practice variation in the use of inotropes following congenital heart surgery.
methodsWe developed an online survey regarding the postoperative use of inotropes. We sent an invitation to all 197 registered members of the Pediatric Cardiac Intensive Care Society (PCICS) to participate in the survey. We also performed a systematic review of the literature.
resultsNinety-eight people (50%) responded, representing 62 international centers. Milrinone is routinely used perioperatively by 90 respondents (97%). Adrenaline/epinephrine is routinely used by 43%, dopamine by 36%, dobutamine by 11%, and levosimendan by 6%. Steroids are used routinely by 54% before initiating cardiopulmonary bypass. Vasopressin is used by 44% of respondents. The development of LCOS is monitored with lactate in 99% of respondents, physical examination (98%), intermittent mixed venous saturation (76%), continuous mixed venous saturation (13%), echocardiography (53%), core-peripheral temperature gap (29%), near-infrared spectrometry (25%), and 4% use cardiac output monitors (PiCCO, USCOM). To improve cardiac output, 42% add/increase milrinone, 37% add adrenaline, and 15% add dopamine. Rescue therapy is titrated individually, based on the patients' pathophysiology. A systematic review of the literature failed to show compelling evidence with regard to the benefit of inotropes.
conclusionsDespite the lack of sufficient evidence, milrinone is used by the vast majority of caregivers following congenital heart surgery.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.