Evidence map›Paper›PMID 29093169›Full record

ArticleJournal of neurophysiology2018

Age- and speed-dependent modulation of gaits in DSCAM

Louise Thiry, Maxime Lemieux, Frédéric Bretzner

Abstract read
In one paragraph

Article in Journal of neurophysiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. eNeuro
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Louise ThiryCentre de Recherche du Centre Hospitalier Universitaire de Québec, CHUL-Neurosciences, Quebec City, Quebec , Canada.
Maxime LemieuxCentre de Recherche du Centre Hospitalier Universitaire de Québec, CHUL-Neurosciences, Quebec City, Quebec , Canada.
Frédéric BretznerCentre de Recherche du Centre Hospitalier Universitaire de Québec, CHUL-Neurosciences, Quebec City, Quebec , Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gaits depend on the interplay between distributed spinal neural networks, termed central pattern generators, generating rhythmic and coordinated movements, primary afferents, and descending supraspinal inputs. Recent studies demonstrated that the mouse displays a rich repertoire of gaits. Changes in gaits occur in mutant mice lacking particular neurons or molecular signaling pathways implicated in the normal establishment of these neural networks. Given the role of the Down syndrome cell adherence molecule (DSCAM) to the formation and maintenance of spinal interneuronal circuits and sensorimotor integration, we have investigated its functional contribution to gaits over a wide range of locomotor speeds using freely walking mice. We show in this study that the DSCAM

Indexed as

GaitAgingAnimalsCell Adhesion MoleculesMiceMice, Inbred C57BLMutationPostural BalanceCell Adhesion MoleculesDscam protein, mouseDSCAMlocomotor gaitmousemutant

Identifiers

PMID29093169
PMCPMC5867377

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.