ArticleAsian-Australasian journal of animal sciences2018
Genome-wide association study of carcass weight in commercial Hanwoo cattle.
Article in Asian-Australasian journal of animal sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genomic regions associated with muscularity in beef cattle differ in five contrasting cattle breeds.Genetics, selection, evolution : GSE · 2020Pooled it
- Article
- A Multi-Breed GWAS for Carcass Weight in Jeju Black Cattle and Hanwoo × Jeju Black Crossbreds.Biology · 2025Article
- Genetic Diversity, Admixture, and Selection Signatures in a Rarámuri Criollo Cattle Population Introduced to the Southwestern United States.International journal of molecular sciences · 2025Article
- Article
- Genomic variance partitioning of carcass and meat quality traits in Angus beef cattle.Frontiers in veterinary science · 2025Article
- Weighted single step GWAS reveals genomic regions associated with economic traits in Murrah buffaloes.Animal biotechnology · 2024Article
- Assessment of Genomic Diversity and Selective Pressures in Crossbred Dairy Cattle of Pakistan.Biochemical genetics · 2024Article
- Genome-Wide Detection of Copy Number Variations and Their Potential Association with Carcass and Meat Quality Traits in Pingliang Red Cattle.International journal of molecular sciences · 2024Article
- A transcriptomic analysis of skeletal muscle tissues reveals promising candidate genes and pathways accountable for different daily weight gain in Hanwoo cattle.Scientific reports · 2024Article
- Identification of Missense Variants Affecting Carcass Traits for Hanwoo Precision Breeding.Genes · 2023Article
- Genome-Wide Association Study to Identify QTL for Carcass Traits in Korean Hanwoo Cattle.Animals : an open access journal from MDPI · 2023Article
- Genome-wide association study for carcass weight in pasture-finished beef cattle in Hawai'i.Frontiers in genetics · 2023Article
- Genomic prediction for growth using a low-density SNP panel in dromedary camels.Scientific reports · 2021Article
- Assessing the genetic background and genomic relatedness of red cattle populations originating from Northern Europe.Genetics, selection, evolution : GSE · 2021Article
- Search for Selection Signatures Related to Trypanosomosis Tolerance in African Goats.Frontiers in genetics · 2021Article
- A multi-breed GWAS for morphometric traits in four Beninese indigenous cattle breeds reveals loci associated with conformation, carcass and adaptive traits.BMC genomics · 2020Article
- Article
- Reduction of slaughter age of Hanwoo steers by early genotyping based on meat yield index.Asian-Australasian journal of animal sciences · 2020Article
- Signatures of positive selection underlying beef production traits in Korean cattle breeds.Journal of animal science and technology · 2020Article
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective of the present study was to validate genes and genomic regions associated with carcass weight using a low-density single nucleotide polymorphism (SNP) Chip in Hanwoo cattle breed.
methodsCommercial Hanwoo steers (n = 220) were genotyped with 20K GeneSeek genomic profiler BeadChip. After applying the quality control of criteria of a call rate ≥90% and minor allele frequency (MAF) ≥0.01, a total of 15,235 autosomal SNPs were left for genome-wide association (GWA) analysis. The GWA tests were performed using single-locus mixed linear model. Age at slaughter was fitted as fixed effect and sire included as a covariate. The level of genome-wide significance was set at 3.28×10
resultsBy employing EMMAX approach which is based on a mixed linear model and accounts for population stratification and relatedness, we identified 17 and 16 loci significantly (p<0.001) associated with carcass weight for the additive and dominant models, respectively. The second most significant (p = 0.000049) SNP (ARS-BFGL-NGS-28234) on bovine chromosome 4 (BTA4) at 21 Mb had an allele substitution effect of 43.45 kg. Some of the identified regions on BTA2, 6, 14, 22, and 24 were previously reported to be associated with quantitative trait loci for carcass weight in several beef cattle breeds.
conclusionThis is the first genome-wide association study using SNP chips on commercial Hanwoo steers, and some of the loci newly identified in this study may help to better DNA markers that determine increased beef production in commercial Hanwoo cattle. Further studies using a larger sample size will allow confirmation of the candidates identified in this study.
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