Evidence map›Paper›PMID 29118772›Full record

ArticleCardiorenal medicine2017

One-Year Conservative Care Using Sodium Bicarbonate Supplementation Is Associated with a Decrease in Electronegative LDL in Chronic Kidney Disease Patients: A Pilot Study.

Felipe Rizzetto, Denise Mafra, Ana Beatriz Barra, Gisella Pires de Melo, Dulcinéia Saes Parra Abdalla, Maurilo Leite

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiorenal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Felipe RizzettoDivision of Nutrition, Federal Hospital of Lagoa (FHL), Rio de Janeiro, Brazil.
Denise MafraGraduate Program in Cardiovascular Sciences, Federal Fluminense University (UFF), Niterói, Brazil.
Ana Beatriz BarraDivision of Nephrology, Federal Hospital of Lagoa (FHL), Rio de Janeiro, Brazil.
Gisella Pires de MeloDivision of Nephrology, Federal Hospital of Lagoa (FHL), Rio de Janeiro, Brazil.
Dulcinéia Saes Parra AbdallaSchool of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo, Brazil.
Maurilo LeiteDivision of Nephrology, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
Universidade de São Paulo · BRUniversidade Federal do Rio de Janeiro · BRUniversidade Federal Fluminense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) patients develop metabolic acidosis when approaching stages 3 and 4, a period in which accelerated atherogenesis may ensue. Studies in vitro show that low pH may increase low-density lipoprotein (LDL) oxidation, suggesting a role for chronic metabolic acidosis in atherosclerosis. The present study attempted to evaluate the effects of conservative care using oral sodium bicarbonate (NaHCO

methodsThirty-one CKD patients were followed by a multidisciplinary team during 15 months of care in which 1.0 mmol/kg/day oral NaHCO

resultsAfter 12 months of conservative care, creatinine clearance (MDRD) was kept stable, and serum bicarbonate (HCO

conclusionsConservative care using oral NaHCO

Indexed as

Alkali therapyCardiovascular diseasesChronic kidney diseaseElectronegative LDL

Identifiers

PMID29118772
PMCPMC5662953
OpenAlexW2748828061

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.