Evidence map›Paper›PMID 29119102›Full record

ArticleInternational journal of genomics2017

The Transcriptional Network Structure of a Myeloid Cell: A Computational Approach.

Jesús Espinal-Enríquez, Daniel González-Terán, Enrique Hernández-Lemus

Abstract read
In one paragraph

Article in International journal of genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. ZHX2 in health and disease.Frontiers in oncology · 2022
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jesús Espinal-EnríquezComputational Genomics Division, National Institute of Genomic Medicine, 14610 México City, Mexico.
Daniel González-TeránComputational Genomics Division, National Institute of Genomic Medicine, 14610 México City, Mexico.
Enrique Hernández-LemusComputational Genomics Division, National Institute of Genomic Medicine, 14610 México City, Mexico.ORCID 0000-0002-1872-1397

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the general principles underlying genetic regulation in eukaryotes is an incomplete and challenging endeavor. The lack of experimental information regarding the regulation of the whole set of transcription factors and their targets in different cell types is one of the main reasons to this incompleteness. So far, there is a small set of curated known interactions between transcription factors and their downstream genes. Here, we built a transcription factor network for human monocytic THP-1 myeloid cells based on the experimentally curated

Identifiers

PMID29119102
PMCPMC5651161

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.