Evidence map›Paper›PMID 29119565›Full record

ReviewThe Journal of physiology2018

Non-invasive methods for the assessment of brown adipose tissue in humans.

Maria Chondronikola, Scott C Beeman, Richard L Wahl

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in The Journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06916208 (Study of the Effect of Capsinoid Supplementation on Brown Adipose Tissue in Obese Adolescents), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06916208 narecruitingnot on this mapstarted 2025, after this paper: background citation

Study of the Effect of Capsinoid Supplementation on Brown Adipose Tissue in Obese Adolescents

TypeinterventionalSponsorUniversity of AvignonRan2025 to 2027Enrolled38ConditionsObese Adolescents, Exercise, Diet Modification, Dietary SupplementArmscapsinoid supplementation, Control group (placebo)
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. [Communications biology · 2024
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Molecular Imaging of Brown Adipose Tissue Mass.International journal of molecular sciences · 2021
    Review
  17. [Comparison ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Maria ChondronikolaCenter for Human Nutrition, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0002-7762-065X
Scott C BeemanDepartment of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA.
Richard L WahlDepartment of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA.
Mallinckrodt (United States) · USWashington University in St. Louis · US

Funding

Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Jonathan R Brestoff · 1999 to 2026
$30.2M
Multi-Modality Quantitiative Imaging for Evaluation of Response to Cancer TherapyU01CA140204 · NCI · JOHNS HOPKINS UNIVERSITY · PI DU, YONG, SOLNES, LILJA · 2011 to 2022
$6.1M
MR ADIPOSE-O2 QUANTIFICATION AND THE HYPOXIA-DRIVEN INSULIN RESISTANCE HYPOTHESISK01DK109119 · NIDDK · WASHINGTON UNIVERSITY · PI BEEMAN, SCOTT CHARLES · 2016 to 2020
$652k
NCI NIH HHS U01 CA140204NIDDK NIH HHS K01 DK109119NIDDK NIH HHS P30 DK056341
6 · The paper itself

Abstract

Brown adipose tissue (BAT) is a recently rediscovered tissue in people that has shown promise as a potential therapeutic target against obesity and its metabolic abnormalities. Reliable non-invasive assessment of BAT volume and activity is critical to allow its importance in metabolic control to be evaluated. Positron emission tomography/computed tomography (PET/CT) in combination with 2-deoxy-2-[

Indexed as

Adipose Tissue, BrownAnimalsDiagnostic ImagingHumansImage Processing, Computer-AssistedMetabolic DiseasesObesitybrown adipose tissueimagingmagnetic resonance imagingmetabolismmethodsPETtemperature

Identifiers

PMID29119565
PMCPMC5792561
OpenAlexW2792675514

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.