Evidence map›Paper›PMID 29124396›Full record

SynthesisRheumatology international2018

Infections and the risk of psoriatic arthritis among psoriasis patients: a systematic review.

Telma Thrastardottir, Thorvardur Jon Love

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Rheumatology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. The Role of Epigenetic Factors in the Pathogenesis of Psoriasis.International journal of molecular sciences · 2024
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Telma ThrastardottirCenter of Public Health Sciences, Faculty of Medicine, University of Iceland, Sturlugotu 8, 101, Reykjavik, Iceland. tth5@hi.is.ORCID http://orcid.org/0000-0002-5997-3398
Thorvardur Jon LoveCenter of Public Health Sciences, Faculty of Medicine, University of Iceland, Sturlugotu 8, 101, Reykjavik, Iceland.ORCID http://orcid.org/0000-0002-2680-6120
University of Iceland · IS

Funding

Icelandic Research Fund RANNIS #120433021
6 · The paper itself

Abstract

Psoriasis and psoriatic arthritis (PsA) are related inflammatory diseases with some shared genetic and environmental risk factors. It has been suggested that environmental factors, including infections, can trigger the development of PsA among psoriasis patients. The aim of this review was to systematically examine available data evaluating the effect of infections on the risk of developing PsA. A systematic search of the Cochrane Library, PubMed, Scopus, and Web of Science was conducted on March 16 2017, in accordance with the PRISMA statement. The following search terms were used along with "psoriatic arthritis": "infections", "risk", "bacteria", and "virus". Abstracts were reviewed and publications meeting the following criteria included: (1) Observational studies on psoriasis and PsA patients, including case-control, cohort, or ecologic studies and (2) presenting original data on the association between infections and PsA. The protocol for this systematic review was registered on PROSPERO (ID: 79432). Twenty-seven original studies presenting data on infections among PsA patients were included. Eight studies showed a statistically significant association between infections and PsA. In addition, seven studies reported mixed result with some statistically significant associations and five studies did not find statistically significant associations. This included studies of bacterial as well as viral pathogens and those of infections in general. The remaining seven studies lacked data to determine statistical significance. Out of all included studies, the total number of included patients was 933 PsA patients and 1611 controls. While the studies summarized did not all provide evidence supporting an association between infections and PsA certain trends emerged. The available data are inconsistent and further studies are needed to verify or refute this purported association. In particular, laryngeal infections and infections involving streptococci should be studied more carefully.

Indexed as

Adaptor Proteins, Signal TransducingArthritis, PsoriaticCohort StudiesCross-Sectional StudiesHumansInflammationLeukocytes, MononuclearPsoriasisAdaptor Proteins, Signal TransducingTAB3 protein, humanAnd psoriasisInfectionsPsoriatic arthritisRisk

Identifiers

PMID29124396
OpenAlexW2767730146

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.