Evidence map›Paper›PMID 29127210›Full record

ArticleRNA (New York, N.Y.)2018

HIV-1 NC-induced stress granule assembly and translation arrest are inhibited by the dsRNA binding protein Staufen1.

Shringar Rao, Alessandro Cinti, Abdelkrim Temzi, Raquel Amorim, Ji Chang You, Andrew J Mouland

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

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  17. Strategies for Success. Viral Infections and Membraneless Organelles.Frontiers in cellular and infection microbiology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Shringar RaoHIV-1 RNA Trafficking Laboratory, Lady Davis Institute at the Jewish General Hospital, Montréal, Québec, H3T 1E2, Canada.
Alessandro CintiHIV-1 RNA Trafficking Laboratory, Lady Davis Institute at the Jewish General Hospital, Montréal, Québec, H3T 1E2, Canada.
Abdelkrim TemziHIV-1 RNA Trafficking Laboratory, Lady Davis Institute at the Jewish General Hospital, Montréal, Québec, H3T 1E2, Canada.
Raquel AmorimHIV-1 RNA Trafficking Laboratory, Lady Davis Institute at the Jewish General Hospital, Montréal, Québec, H3T 1E2, Canada.
Ji Chang YouNational Research Laboratory of Molecular Virology, Department of Pathology, School of Medicine, The Catholic University of Korea, Seocho-gu Banpo-dong 505, Seoul 137-701, Republic of Korea.
Andrew J MoulandHIV-1 RNA Trafficking Laboratory, Lady Davis Institute at the Jewish General Hospital, Montréal, Québec, H3T 1E2, Canada.
Jewish General Hospital · CACatholic University of Korea · KR

Funding

CIHR MOP-38111
6 · The paper itself

Abstract

The nucleocapsid (NC) is an N-terminal protein derived from the HIV-1 Gag precursor polyprotein, pr55

Indexed as

Protein BiosynthesisCell LineCytoplasmic GranulesDNA HelicaseseIF-2 KinaseEukaryotic Initiation Factor-2Eukaryotic Initiation Factor-3gag Gene Products, Human Immunodeficiency VirusHeLa CellsHIV-1HumansPoly-ADP-Ribose Binding ProteinsRNA-Binding ProteinsRNA HelicasesRNA, MessengerRNA Recognition Motif ProteinsDNA HelicaseseIF-2 KinaseEukaryotic Initiation Factor-2Eukaryotic Initiation Factor-3G3BP1 protein, humangag Gene Products, Human Immunodeficiency VirusNCP7 protein, Human immunodeficiency virus 1Poly-ADP-Ribose Binding ProteinsRNA-Binding ProteinsRNA HelicasesRNA, MessengerRNA Recognition Motif ProteinsHIV-1mRNA translationnucleocapsidStaufen1stress granules

Identifiers

PMID29127210
PMCPMC5769749
OpenAlexW2767936334

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.