Evidence map›Paper›PMID 29181786›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2019

Early therapeutic effects of adaptive servo-ventilation on cardiac sympathetic nervous function in patients with heart failure evaluated using a combination of

Yusuke Tokuda, Mamoru Sakakibara, Keiichiro Yoshinaga, Shiro Yamada, Kiwamu Kamiya, Naoya Asakawa, Takashi Yoshitani, Keiji Noguchi, Osamu Manabe, Nagara Tamaki and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. The prognostic value ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Pooled it
  2. European journal of nuclear medicine and molecular imaging · 2023
    Review
  3. Article
  4. Review
  5. Cardiac adrenergic neuronal activity, sleep apnea, and potential therapeutic role of nocturnal ventilatory assistance in patients with heart failure.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  6. How do we establish cardiac sympathetic nervous system imaging withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Yusuke TokudaDepartment of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo, 060-8638, Japan.
Mamoru SakakibaraDepartment of Cardiovascular Medicine, Tokyo Tenshi Hospital, Tokyo, Japan.
Keiichiro YoshinagaDiagnostic and Therapeutic Nuclear Medicine, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-Ku, Chiba, 263-8555, Japan. yoshinaga.keiichiro@qst.go.jp.
Shiro YamadaDepartment of Cardiovascular Medicine, Otaru Kyokai Hospital, Otaru, Japan.
Kiwamu KamiyaDepartment of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo, 060-8638, Japan.
Naoya AsakawaDepartment of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo, 060-8638, Japan.
Takashi YoshitaniDepartment of Cardiovascular Medicine, Hakodate Neurosurgery Hospital, Hakodate, Japan.
Keiji NoguchiDepartment of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo, 060-8638, Japan.
Osamu ManabeDepartment of Nuclear Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Nagara TamakiDepartment of Nuclear Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Hiroyuki TsutsuiDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Hokkaido University · JPHakodate National Hospital · JPKyushu University · JPTenshi Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleAdaptive servo-ventilation (ASV), a novel respiratory support therapy for sleep disorders, may improve cardiac function in heart failure (HF). However, the reasons that ASV improves cardiac function have not been fully studied especially in sympathetic nervous function (SNF). The purpose of the present study was to investigate the effects of ASV therapy on cardiac SNF in patients with HF.

methodsWe evaluated ASV therapeutic effects before and 6 months after ASV therapy in 9 HF patients [57.3 ± 17.3 years old, left ventricular ejection fraction (LVEF) 36.1 ± 16.7%]. We performed echocardiography, polysomnography, biomarkers,

resultsASV therapy reduced apnea-hypopnea index (AHI) and improved plasma brain natriuretic peptide (BNP) concentration. In

conclusionsASV reduced AHI and improved BNP. ASV might initially improve presynaptic cardiac sympathetic nervous function in HF patients after 6 months of treatment.

Indexed as

Positron-Emission TomographyRespiration, ArtificialTomography, Emission-Computed, Single-Photon3-IodobenzylguanidineAdultAgedApneaCarbon IsotopesEchocardiographyEphedrineFemaleHeart FailureHumansIodine RadioisotopesMaleMiddle Aged3-hydroxyephedrine3-IodobenzylguanidineCarbon IsotopesEphedrineIodine RadioisotopesNatriuretic Peptide, Brain11C-hydroxyephedrine123I-metaiodobenzylguanidineadaptive servo-ventilationcardiac sympathetic nerve functionheart failuretomography

Identifiers

PMID29181786
PMCPMC6660491
OpenAlexW2770780223

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.