Evidence map›Paper›PMID 29183963›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2018

Distinct moieties underlie biphasic H

Carolina D Garciarena, Akif Malik, Pawel Swietach, Alonso P Moreno, Richard D Vaughan-Jones

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Acid-Base Basics.Seminars in nephrology · 2019
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Carolina D GarciarenaDepartment of Physiology, Anatomy and Genetics, Burdon Sanderson Cardiac Science Centre, University of Oxford, Oxford, United Kingdom.
Akif MalikDepartment of Physiology, Anatomy and Genetics, Burdon Sanderson Cardiac Science Centre, University of Oxford, Oxford, United Kingdom.
Pawel SwietachDepartment of Physiology, Anatomy and Genetics, Burdon Sanderson Cardiac Science Centre, University of Oxford, Oxford, United Kingdom.
Alonso P MorenoNora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, USA.
Richard D Vaughan-JonesDepartment of Physiology, Anatomy and Genetics, Burdon Sanderson Cardiac Science Centre, University of Oxford, Oxford, United Kingdom.
Science Oxford · GBRoyal College of Surgeons in Ireland · IEUniversity of Oxford · GBUniversity of Utah · US

Funding

Permeability of heteromeric heart gap junction channelsR01HL063969 · NHLBI · UNIVERSITY OF UTAH · PI MORENO, ALONSO P · 2000 to 2007
$2.6M
British Heart Foundation RG/08/016/26423British Heart Foundation RG/15/9/31534NHLBI NIH HHS R01 HL063969
6 · The paper itself

Abstract

Most mammalian cells can intercommunicate via connexin-assembled, gap-junctional channels. To regulate signal transmission, connexin (Cx) channel permeability must respond dynamically to physiological and pathophysiological stimuli. One key stimulus is intracellular pH (pH

Indexed as

Ion Channel GatingProtonsAnimalsCell CommunicationConnexin 43HeLa CellsHumansHydrogen-Ion ConcentrationMiceConnexin 43Protonsacid–basebrainelectrical synapsegap junctionsheart

Identifiers

PMID29183963
PMCPMC5893178
OpenAlexW2768609397

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.