Trial reportEuropean journal of applied physiology2018
Effects of supervised exercise training on lower-limb cutaneous microvascular reactivity in adults with venous ulcers.
Trial report in European journal of applied physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Compression therapies for venous leg ulcers: The VENous Ulcer Study 6 (VenUS 6), an open, multicentre, randomised clinical trial.PLoS medicine · 2026Trial
- Medium- and longer-term cardiovascular effects of e-cigarettes in adults making a stop-smoking attempt: a randomized controlled trial.BMC medicine · 2022Trial
- A Lower Leg Physical Activity Intervention for Individuals With Chronic Venous Leg Ulcers: Randomized Controlled Trial.JMIR mHealth and uHealth · 2020Trial
- Supervised exercise training as an adjunct therapy for venous leg ulcers: a randomized controlled feasibility trial.The British journal of dermatology · 2018Trial
- Impact of physical activity as an adjuvant treatment in the healing of venous ulcers in primary care: active legs RCT.BMC nursing · 2025Article
- A Multicenter, Randomized, Controlled, Clinical Trial Evaluating a Lyopreserved Amniotic Membrane in the Treatment of Venous Leg Ulcers.Health science reports · 2025Article
- Benefit in physical function and quality of life to nonsurgical treatment of varicose veins: Pilot study.World journal of clinical cases · 2024Article
- Active legs: Impact of physical activity as an adjuvant treatment in the healing of venous ulcers in primary care: a RCT protocol study.BMC nursing · 2023Article
- Effects of Oral Nutritional Supplementation on Patients with Venous Ulcers: A Clinical Trial.Journal of clinical medicine · 2022Article
- Short-Term Cardiovascular Effects of E-Cigarettes in Adults Making a Stop-Smoking Attempt: A Randomized Controlled Trial.Biology · 2021Article
- Physical Activity as an Adjunct to Compression Therapy on Healing Outcomes and Recurrence in Patients With Venous Leg Ulcers: A Scoping Review Protocol.Frontiers in medicine · 2021Article
- The Physics of Fluid Dynamics Applied to Vascular Ulcers and Its Impact on Nursing Care.Healthcare (Basel, Switzerland) · 2020Article
- Article
- Participant experiences in a feasibility trial of supervised exercise training in adults with venous leg ulcers: A qualitative study.International wound journal · 2019Article
- Combined effect of yoga and naturopathy in uncomplicated varicose vein disease - a prospective randomized controlled trial.Journal of Ayurveda and integrative medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
purposeTo investigate the effects of a 12-week supervised exercise programme on lower-limb cutaneous microvascular reactivity in adults with venous leg ulceration.
methodsThirty-eight adults with unilateral venous ulceration who were being treated with lower-limb compression therapy (58% male; mean age 65 years; median ulcer size 5 cm
resultsThirty-seven participants completed follow-up assessments. Median session attendance was 36 (range 2-36). Analyses of covariance revealed greater peak CVC responses to ACh in the exercise group at 3 months in both the ulcerated (adjusted difference = 0.944 AU/mmHg; 95% CI 0.504-1.384) and non-ulcerated (adjusted difference = 0.596 AU/mmHg; 95% CI 0.028-1.164) legs. Peak CVC responses to SNP were also greater in the exercise group at 3 months in the ulcerated leg (adjusted difference = 0.882 AU/mmHg; 95% CI 0.274-1.491), but not the non-ulcerated leg (adjusted difference = 0.392 AU/mmHg; 95% CI - 0.377 to 1.161).
conclusionSupervised exercise training improves lower-limb cutaneous microvascular reactivity in adults with venous leg ulceration.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.