Evidence mapPaperPMID 29219149Full record

ReviewNature reviews. Endocrinology2018

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications.

Yan Zheng, Sylvia H Ley, Frank B Hu

8 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 2,626 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2,626citing papers in PubMed, 8 pooled it
178.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05310916 phase3unknown statusstarted 2022, after this paper: background citation

Evaluation of the Effect of Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors on Diabetic Retinopathy in Patients With Type 2 Diabetes Mellitus

Ran2022Enrolled60Registered outcomes3Posted comparisons0ConditionsDiabetic RetinopathyArmsDapagliflozin 10mg Tab plus another oral hypoglycemic agent, Two oral hypoglycemic agents other than dapagliflozin
Open the trial in the graph
NCT03939000 completednot on this map

Clinical Profile and Laboratory Finding of Diabetic Foot Ulcers From Tertiary Hospitals in Bali

TypeobservationalSponsorUdayana UniversityRan2016 to 2019Enrolled113ConditionsDiabetic Foot Ulcer, Type 2 Diabetes Mellitus, Laboratory Problem, Physical Findings.Skin Ulcer
NCT04532385 nacompletednot on this map

Effect of a 12-week Administration of Green Tea Extract on Lipids in Patients With Type 2 Diabetes

TypeinterventionalSponsorCentro Universitario de Ciencias de la Salud, MexicoRan2018 to 2019Enrolled20ConditionsDiabetes Mellitus, Type 2, Dyslipidemias, Arterial StiffnessArmsGreen tea extract, Placebo
NCT05532553 unknown statusnot on this mapstarted 2022, after this paper: background citation

Association Between Carotid Atherosclerosis and Fatty Liver Index in Patients With Type 2 Diabetes Mellitus

TypeobservationalSponsorAssiut UniversityRan2022 to 2023Enrolled200ConditionsAtherosclerosis With Diabetes Mellitus and Fatty LiverArmsCarotid Doppler U/S
NCT05602532 unknown statusnot on this mapstarted 2022, after this paper: background citation

Triglyceride-Glucose Index in Diabetic Nephropathy in Type 2diaberes Mellitus Patients

TypeobservationalSponsorAssiut UniversityRan2022 to 2023Enrolled100ConditionsDiabetes Mellitus, Type 2
NCT06401122 unknown statusnot on this mapstarted 2024, after this paper: background citation

Comparison of Dyslipidemia Among Diabetics Versus Non Diabetics in Haemodialysis

TypeobservationalSponsorAssiut UniversityRan2024 to 2025Enrolled100ConditionsDyslipidemiasArmshaemodialysis
NCT06478173 nacompletednot on this mapstarted 2024, after this paper: background citation

The Effect of Complex Exercise Training on General Health Status in Patients with Type 2 Diabetes

TypeinterventionalSponsorUniversity of the Faroe IslandsRan2024 to 2024Enrolled126ConditionsType2diabetesArmsExercise training
NCT06562842 narecruitingnot on this mapstarted 2025, after this paper: background citation

The Effects of Regular Exercise on Gut Microbiota Composition in Individuals with Type 2 Diabetes

TypeinterventionalSponsorUniversity of ThessalyRan2025 to 2026Enrolled60ConditionsType 2 DiabetesArmsRegular exercise, Control comparator
3 · Its place in the literature

Who cites it

2,626 citing papers in PubMed, 8 syntheses or guidelines pooled it, 5,575 citations in OpenAlex.

  1. Pooled it
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  15. Gut microbes · 2026
    Article
  16. Article
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2,566 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yan ZhengState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, 2005 Songhu Road, Shanghai, China.
Sylvia H LeyDepartment of Nutrition, Harvard T.H. Chan School of Public Health, 2005 Songhu Road, Shanghai, China.
Frank B HuDepartment of Nutrition, Harvard T.H. Chan School of Public Health, 2005 Songhu Road, Shanghai, China.
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Globally, the number of people with diabetes mellitus has quadrupled in the past three decades, and diabetes mellitus is the ninth major cause of death. About 1 in 11 adults worldwide now have diabetes mellitus, 90% of whom have type 2 diabetes mellitus (T2DM). Asia is a major area of the rapidly emerging T2DM global epidemic, with China and India the top two epicentres. Although genetic predisposition partly determines individual susceptibility to T2DM, an unhealthy diet and a sedentary lifestyle are important drivers of the current global epidemic; early developmental factors (such as intrauterine exposures) also have a role in susceptibility to T2DM later in life. Many cases of T2DM could be prevented with lifestyle changes, including maintaining a healthy body weight, consuming a healthy diet, staying physically active, not smoking and drinking alcohol in moderation. Most patients with T2DM have at least one complication, and cardiovascular complications are the leading cause of morbidity and mortality in these patients. This Review provides an updated view of the global epidemiology of T2DM, as well as dietary, lifestyle and other risk factors for T2DM and its complications.

Indexed as

Diabetes ComplicationsDietDisease ManagementLife StyleDiabetes Mellitus, Type 2Global HealthHumansMorbidityRisk Factors

Identifiers

PMID29219149
OpenAlexW2774743973

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.