Evidence map›Paper›PMID 29243387›Full record

ArticleMicrobiologyOpen2018

Investigation of Cryptococcus neoformans magnesium transporters reveals important role of vacuolar magnesium transporter in regulating fungal virulence factors.

Chen-Hao Suo, Lan-Jing Ma, Hai-Long Li, Jian-Fang Sun, Chao Li, Ming-Hui Lin, Tian-Shu Sun, Wei Du, Yan-Jian Li, Xin-Di Gao and 3 more

Open access · goldAbstract read
In one paragraph

Article in MicrobiologyOpen, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. The roles ofFrontiers in medicine · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Chen-Hao SuoCollege of Life and Health Sciences, Northeastern University, Liaoning, Shenyang, China.
Lan-Jing MaCollege of Life and Health Sciences, Northeastern University, Liaoning, Shenyang, China.
Hai-Long LiCollege of Life and Health Sciences, Northeastern University, Liaoning, Shenyang, China.
Jian-Fang SunCollege of Life and Health Sciences, Northeastern University, Liaoning, Shenyang, China.
Chao LiCollege of Life and Health Sciences, Northeastern University, Liaoning, Shenyang, China.
Ming-Hui LinCollege of Life and Health Sciences, Northeastern University, Liaoning, Shenyang, China.
Tian-Shu SunCollege of Life and Health Sciences, Northeastern University, Liaoning, Shenyang, China.
Wei DuCollege of Life and Health Sciences, Northeastern University, Liaoning, Shenyang, China.
Yan-Jian LiCollege of Life and Health Sciences, Northeastern University, Liaoning, Shenyang, China.
Xin-Di GaoCollege of Life and Health Sciences, Northeastern University, Liaoning, Shenyang, China.
Yang MengCollege of Life and Health Sciences, Northeastern University, Liaoning, Shenyang, China.
Si-Xiang SaiSchool of Medicine, Binzhou Medical University, Yantai, Shandong, China.
Chen DingCollege of Life and Health Sciences, Northeastern University, Liaoning, Shenyang, China.ORCID 0000-0002-9195-2255
Northeastern University · CNBinzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptococcus neoformans is an important opportunistic fungal pathogen in humans. Recent studies have demonstrated that metals are critical factors for the regulation of fungal virulence in hosts. In this study, we systemically investigated the function of C. neoformans magnesium transporters in controlling the intracellular Mg balance and virulence-associated factors. We identified three Mg transporters in C. neoformans: Mgt1, Mgt2, and Mgt3. While we could not detect a Mg

Indexed as

Gene Expression Regulation, FungalCation Transport ProteinsCryptococcus neoformansGene Expression ProfilingGene Knockout TechniquesMagnesiumMembrane Transport ProteinsSaccharomyces cerevisiae ProteinsSequence HomologyVacuolesVirulence FactorsCation Transport ProteinsMagnesiumMembrane Transport ProteinsMNR2 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsVirulence FactorsCapsuleCryptococcus neoformansmelaninMg homeostasis

Identifiers

PMID29243387
PMCPMC6011977
OpenAlexW2774135047

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.