Evidence map›Paper›PMID 29247493›Full record

ReviewMicrocirculation (New York, N.Y. : 1994)2018

The yin and yang of K

Masayo Koide, Arash Moshkforoush, Nikolaos M Tsoukias, David C Hill-Eubanks, George C Wellman, Mark T Nelson, Fabrice Dabertrand

Open access · greenAbstract readReview
In one paragraph

Review in Microcirculation (New York, N.Y. : 1994), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. PIPProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  4. Review
  5. Prostaglandin EFrontiers in aging neuroscience · 2021
    Article
  6. Article
  7. The Ion Channel and GPCR Toolkit of Brain Capillary Pericytes.Frontiers in cellular neuroscience · 2020
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Masayo KoideDepartment of Pharmacology, University of Vermont, Burlington, VT, USA.
Arash MoshkforoushDepartment of Biomedical Engineering, Florida International University, Miami, FL, USA.
Nikolaos M TsoukiasDepartment of Biomedical Engineering, Florida International University, Miami, FL, USA.
David C Hill-EubanksDepartment of Pharmacology, University of Vermont, Burlington, VT, USA.
George C WellmanDepartment of Pharmacology, University of Vermont, Burlington, VT, USA.
Mark T NelsonDepartment of Pharmacology, University of Vermont, Burlington, VT, USA.
Fabrice DabertrandDepartment of Pharmacology, University of Vermont, Burlington, VT, USA.ORCID 0000-0003-2541-9185
University of Vermont · USFlorida International University · US

Funding

Impact of SAH on Parenchymal Arterioles and Neurovascular CouplingP01HL095488 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BONEV, ADRIAN · 2010 to 2014
$11.4M
Capillary control of cerebral blood flow, and its disruption in small vessel diseaseR01HL136636 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI Fabrice Dabertrand · 2017 to 2026
$3.8M
Ca2+ Sparks and Urinary Bladder Smooth Muscle ExcitabilityR37DK053832 · NIDDK · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI NELSON, MARK T · 2008 to 2017
$3.4M
Regulations of Myoendothelial Function By Signaling Microdomains in HypertensionR01HL121706 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI NELSON, MARK T · 2014 to 2017
$1.6M
K+ sensing & electrical signaling by Kir channels in brain vasculatureR01HL131181 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI NELSON, MARK T · 2016 to 2018
$1.4M
NHLBI NIH HHS P01 HL095488NHLBI NIH HHS R01 HL121706NHLBI NIH HHS R01 HL131181NHLBI NIH HHS R01 HL136636NIDDK NIH HHS R37 DK053832
6 · The paper itself

Abstract

Cerebral SVDs encompass a group of genetic and sporadic pathological processes leading to brain lesions, cognitive decline, and stroke. There is no specific treatment for SVDs, which progress silently for years before becoming clinically symptomatic. Here, we examine parallels in the functional defects of PAs in CADASIL, a monogenic form of SVD, and in response to SAH, a common type of hemorrhagic stroke that also targets the brain microvasculature. Both animal models exhibit dysregulation of the voltage-gated potassium channel, K

Indexed as

AnimalsCADASILDilatationHumansMicrovesselsPotassium Channels, Voltage-GatedSubarachnoid HemorrhagePotassium Channels, Voltage-GatedCADASILcerebral blood flowcerebral small vessel diseasesubarachnoid hemorrhagevoltage-gated potassium channel

Identifiers

PMID29247493
PMCPMC5760473
OpenAlexW2771992385

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.