Evidence mapPaperPMID 29248197Full record

ArticleGynecologic oncology2018

Significance of venous thromboembolism in women with uterine carcinosarcoma.

Koji Matsuo, Malcolm S Ross, Dwight D Im, Merieme M Klobocista, Stephen H Bush, Marian S Johnson, Tadao Takano, Erin A Blake, Yuji Ikeda, Masato Nishimura and 21 more

Abstract readMulticenter Study
In one paragraph

Article in Gynecologic oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

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  14. Construction and Validation of a Nomogram to Predict the Postoperative Venous Thromboembolism Risk in Patients with HGSOC.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 20 institutions in 2 countries.

Koji MatsuoDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Southern California, CA, USA. Electronic address: koji.matsuo@med.usc.edu.
Malcolm S RossDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Magee-Womens Hospital, University of Pittsburgh, PA, USA.
Dwight D ImThe Gynecologic Oncology Center, Mercy Medical Center, Baltimore, MD, USA.
Merieme M KlobocistaDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Albert Einstein College of Medicine, Montefiore Medical Center, NY, USA.
Stephen H BushDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Moffitt Cancer Center, University of South Florida, FL, USA.
Marian S JohnsonDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kentucky, KY, USA.
Tadao TakanoDepartment of Obstetrics and Gynecology, Tohoku University, Miyagi, Japan.
Erin A BlakeDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Colorado, CO, USA.
Yuji IkedaDepartment of Obstetrics and Gynecology, The University of Tokyo, Tokyo, Japan.
Masato NishimuraDepartment of Obstetrics and Gynecology, Tokushima University, Tokushima, Japan.
Yutaka UedaDepartment of Obstetrics and Gynecology, Osaka University, Osaka, Japan.
Masako ShidaDepartment of Obstetrics and Gynecology, Tokai University, Kanagawa, Japan.
Kosei HasegawaDepartment of Obstetrics and Gynecology, Saitama Medical University International Medical Center, Saitama, Japan.
Tsukasa BabaDepartment of Obstetrics and Gynecology, Kyoto University, Kyoto, Japan.
Sosuke AdachiDepartment of Obstetrics and Gynecology, Niigata University, Niigata, Japan.
Takuhei YokoyamaDepartment of Obstetrics and Gynecology, Osaka Rosai Hospital, Osaka, Japan.
Shinya SatohDepartment of Obstetrics and Gynecology, Tottori University, Tottori, Japan.
Hiroko MachidaDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Southern California, CA, USA.
Shiori YanaiDepartment of Obstetrics and Gynecology, Kurashiki Medical Center, Okayama, Japan.
Keita IwasakiDepartment of Obstetrics and Gynecology, Aichi Medical University, Aichi, Japan.
Takahito M MiyakeDepartment of Obstetrics and Gynecology, Kawasaki Medical School, Okayama, Japan.
Satoshi TakeuchiDepartment of Obstetrics and Gynecology, Iwate Medical University, Morioka, Japan.
Munetaka TakekumaDepartment of Gynecology, Shizuoka Cancer Center, Shizuoka, Japan.
Tadayoshi NaganoDepartment of Obstetrics and Gynecology, Kitano Hospital, Osaka, Japan.
Mayu YunokawaDepartment of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.
Tanja PejovicDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Oregon Health & Science University, OR, USA.
Kohei OmatsuDepartment of Gynecology, Cancer Institute Hospital, Tokyo, Japan.
Mian M K ShahzadDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Moffitt Cancer Center, University of South Florida, FL, USA.
Joseph L KelleyDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Magee-Womens Hospital, University of Pittsburgh, PA, USA.
Frederick R UelandDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kentucky, KY, USA.
Lynda D RomanDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Southern California, CA, USA.
University of Southern California · USUniversity of Kentucky · USUniversity of Pittsburgh · USUniversity of South Florida · USAichi Medical University · JPAlbert Einstein College of Medicine · USIwate Medical University · JPKawasaki Medical School · JPKitano Hospital · JPKurashiki Medical Center · JPKyoto University · JPMercy Medical Center · USNiigata University · JPOregon Health & Science University · USOsaka Rosai Hospital · JPSaitama Medical University · JPShizuoka Cancer Center · JPThe Cancer Institute Hospital · JPThe University of Osaka · JPThe University of Tokyo · JP

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · 1985 to 2025
$66.6M
NCI NIH HHS P30 CA014089
6 · The paper itself

Abstract

objectiveTo identify risk factors for venous thromboembolism (VTE) and to examine the association of VTE and survival in women with uterine carcinosarcoma.

methodsThis multicenter retrospective study examined 906 women who underwent primary surgical treatment for stage I-IV uterine carcinosarcoma. Time-dependent analyses were performed for cumulative incidence of VTE after surgery on multivariate models.

resultsThere were 72 (7.9%) women who developed VTE after surgery with 1-, 2-, and 5-year cumulative incidences being 5.1%, 7.3%, and 10.2%, respectively. On multivariate analysis, older age (hazard ratio [HR] per year 1.03, P=0.012), non-Asian race (HR 6.28, P<0.001), large body habitus (HR per kg/m

conclusionOur study suggests that VTE represents a surrogate marker of aggressive tumor behavior and diminished patient condition in uterine carcinosarcoma; obese Non-Asian women with large tumors carry a disproportionally high risk of VTE, suggesting that long-term prophylaxis may benefit this population.

Indexed as

AgedCarcinosarcomaFemaleHumansKaplan-Meier EstimateMiddle AgedNeoplasm MetastasisNeoplasm, ResidualPostoperative ComplicationsRetrospective StudiesRisk FactorsTumor BurdenUterine NeoplasmsVenous ThromboembolismDeep vein thrombosisPulmonary embolismRisk factorsSurvivalUterine carcinosarcomaVenous thromboembolism

Identifiers

PMID29248197
PMCPMC7529359
OpenAlexW2773970508

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.