Evidence map›Paper›PMID 29255490›Full record

ArticleGut pathogens2017

Exposure to environmental microbiota explains persistent abdominal pain and irritable bowel syndrome after a major flood.

NurFadhilah Yusof, Nurhazwani Hamid, Zheng Feei Ma, Rona Marie Lawenko, Wan Mohd Zahiruddin Wan Mohammad, Deirdre A Collins, Min Tze Liong, Toshitaka Odamaki, Jinzhong Xiao, Yeong Yeh Lee

Open access · goldAbstract read
In one paragraph

Article in Gut pathogens, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Altered molecular signature of the intestinal microbiota in irritable bowel syndrome patients versus healthy controls: An updated systematic review.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Pooled it
  2. Pooled it
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  4. Review
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  7. Infants exposedmSphere · 2023
    Article
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  11. The Probiotic VSL#3Pharmaceuticals (Basel, Switzerland) · 2021
    Article
  12. Age andMicroorganisms · 2021
    Article
  13. Validity and Reliability of the Newly Developed Malay-Language Health Belief of Bloating (HB-Bloat) Scale.International journal of environmental research and public health · 2020
    Article
  14. Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 5 countries.

NurFadhilah Yusof *School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan Malaysia.
Nurhazwani Hamid *School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan Malaysia.
Zheng Feei Ma *School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan Malaysia.
Rona Marie LawenkoDe La Salle Health Sciences Institute, Dasmarinas, Cavite Philippines.
Wan Mohd Zahiruddin Wan MohammadSchool of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan Malaysia.
Deirdre A CollinsSchool of Medical and Health Sciences, Edith Cowan University, Perth, Australia.
Min Tze LiongSchool of Industrial Technology, Universiti Sains Malaysia, Gelugor, Penang Malaysia.
Toshitaka OdamakiNext Generation Science Institute, Morinaga Milk Industry Co., Ltd., Tokyo, Japan.
Jinzhong XiaoNext Generation Science Institute, Morinaga Milk Industry Co., Ltd., Tokyo, Japan.
Yeong Yeh LeeSchool of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan Malaysia.ORCID 0000-0002-6486-7717
Hospital Universiti Sains Malaysia · MYMorinaga (Japan) · JPDe La Salle University – Dasmariñas · PHEdith Cowan University · AUUniversiti Sains Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAfter an environmental disaster, the affected community is at increased risk for persistent abdominal pain but mechanisms are unclear. Therefore, our study aimed to determine association between abdominal pain and poor water, sanitation and hygiene (WaSH) practices, and if small intestinal bacterial overgrowth (SIBO) and/or gut dysbiosis explain IBS, impaired quality of life (QOL), anxiety and/or depression after a major flood.

resultsNew onset abdominal pain, IBS based on the Rome III criteria, WaSH practices, QOL, anxiety and/or depression, SIBO (hydrogen breath testing) and stools for metagenomic sequencing were assessed in flood victims. Of 211 participants, 37.9% (

conclusionDisturbed gut microbiota because of environmentally-derived organisms may explain persistent abdominal pain and IBS after a major environmental disaster in the presence of poor WaSH practices.

Indexed as

Abdominal painDysbiosisFloodMalaysiaSanitation and hygiene practicesSmall intestinal bacterial overgrowthWater

Identifiers

PMID29255490
PMCPMC5729606
OpenAlexW2774616244

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.