Evidence map›Paper›PMID 29259381›Full record

ArticleWorld journal of gastroenterology2017

Gender differences in ghrelin, nociception genes, psychological factors and quality of life in functional dyspepsia.

Yoon Jin Choi, Young Soo Park, Nayoung Kim, Yong Sung Kim, Sun Min Lee, Dong Ho Lee, Hyun Chae Jung

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

  1. Female Gender is a Poor Predictive Factor of Functional Dyspepsia Resolution afterThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2018
    Trial
  2. Article
  3. Article
  4. Article
  5. [The Relationship of Dysbiosis of Duodenal Microbiome and Functional Dyspepsia].The Korean journal of helicobacter and upper gastrointestinal research · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Ghrelin mediated regulation of neurosynaptic transmitters in depressive disorders.Current research in pharmacology and drug discovery · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Beneficial Potential ofFrontiers in pharmacology · 2021
    Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yoon Jin ChoiDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi-do 13620, South Korea.
Young Soo ParkDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi-do 13620, South Korea.
Nayoung KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi-do 13620, South Korea.
Yong Sung KimDepartment of Gastroenterology, Wonkwang Digestive Disease Research Institute, Wonkwang University Sanbon Hospital, Gunpo, Gyeonggi-do 1142, South Korea.
Sun Min LeeDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi-do 13620, South Korea.
Dong Ho LeeDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi-do 13620, South Korea.
Hyun Chae JungDepartment of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, 03080, South Korea.
Wonkwang University · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimto evaluate gender differences in the aspect of ghrelin, nociception-related genes and psychological aspects and the quality of life (QoL) in Korean functional dyspepsia (FD) patients.

methodsTotal of 191 persons were prospectively enrolled between March 2013 and May 2016 in Seoul National Bundang Hospital, and classified into control and FD group based on ROME III criteria. Questionnaire included assessment for dyspepsia symptoms, QoL and anxiety or depression. Preproghrelin and nociception genes in the gastric mucosa and plasma acyl/des-acyl ghrelin were measured.

resultsLower level of plasma acyl ghrelin in FD patients compared to control was significant only in male (15.9 fmol/mL

conclusionGender differences of ghrelin and nociception-related genes in male and psychological factors in female underlie FD symptoms. More careful assessment of psychological or emotional status is required particularly for the female FD patients.

Indexed as

Quality of LifeAdultAgedAnxietyDepressionDyspepsiaFemaleGastric MucosaGhrelinHumansMaleMiddle AgedNociceptionProspective StudiesRepublic of KoreaSex FactorsGhrelinFunctional dyspepsiaGender differencesQuality of life

Identifiers

PMID29259381
PMCPMC5725300
OpenAlexW2773462283

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.