ArticleBMC evolutionary biology2017
Various Wolbachia genotypes differently influence host Drosophila dopamine metabolism and survival under heat stress conditions.
Article in BMC evolutionary biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 67 citations in OpenAlex.
- Temperature-sensitive cytoplasmic incompatibility across divergent Wolbachia partly reflects cifB transcription, not endosymbiont density.Molecular biology and evolution · 2026Article
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- Insect Lipid Metabolism in the Presence of Symbiotic and Pathogenic Viruses and Bacteria.Advances in experimental medicine and biology · 2026Review
- Gram-Negative Bacteria Across Spatial Scales: A Meta-Analysis of Ant-Associated Bacterial Communities Under Distinct Environmental Conditions.Ecology and evolution · 2025Article
- "Hostbusters": The Bacterial EndosymbiontInsects · 2025Article
- Wolbachia infection facilitates adaptive increase in male egg size in response to environmental changes.Scientific reports · 2025Article
- Wolbachia modify host cell metabolite profiles in response to short-term temperature stress.Environmental microbiology reports · 2024Article
- Wolbachia supergroup A in Enoplognatha latimana (Araneae: Theridiidae) in Poland as an example of possible horizontal transfer of bacteria.Scientific reports · 2024Article
- Article
- The Effect of Genotype Combinations ofInsects · 2023Article
- Effects of heat tolerance on the gut microbiota of Sarcophaga peregrina (Diptera: Sarcophagidae) and impacts on the life history traits.Parasites & vectors · 2023Article
- Ovarian transcriptional response to Wolbachia infection in D. melanogaster in the context of between-genotype variation in gene expression.G3 (Bethesda, Md.) · 2023Article
- Article
- A wMel Wolbachia variant in Aedes aegypti from field-collected Drosophila melanogaster with increased phenotypic stability under heat stress.Environmental microbiology · 2022Article
- Sodium Benzoate Delays the Development ofFrontiers in microbiology · 2022Article
- Diverse wMel variants of Wolbachia pipientis differentially rescue fertility and cytological defects of the bag of marbles partial loss of function mutation in Drosophila melanogaster.G3 (Bethesda, Md.) · 2021Article
- Wolbachia impairs post-eclosion host preference in a parasitoid wasp.Die Naturwissenschaften · 2021Article
- Spider Mites Singly Infected With EitherFrontiers in microbiology · 2021Article
- Gut Microbiota ofFrontiers in microbiology · 2021Article
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOne of the most widespread prokaryotic symbionts of invertebrates is the intracellular bacteria of Wolbachia genus which can be found in about 50% of insect species. Wolbachia causes both parasitic and mutualistic effects on its host that include manipulating the host reproductive systems in order to increase their transmission through the female germline, and increasing the host fitness. One of the mechanisms, promoting adaptation in biological organisms, is a non-specific neuroendocrine stress reaction. In insects, this reaction includes catecholamines, dopamine, serotonin and octopamine, which act as neurotransmitters, neuromodulators and neurohormones. The level of dopamine metabolism correlates with heat stress resistance in Drosophila adults.
resultsTo examine Wolbachia effect on Drosophila survival under heat stress and dopamine metabolism we used five strains carrying the nuclear background of interbred Bi90 strain and cytoplasmic backgrounds with different genotype variants of Wolbachia (produced by 20 backcrosses of Bi90 males with appropriate source of Wolbachia). Non-infected Bi90 strain (treated with tetracycline for 3 generations) was used as a control group. We demonstrated that two of five investigated Wolbachia variants promote changes in Drosophila heat stress resistance and activity of enzymes that produce and degrade dopamine, alkaline phosphatase and dopamine-dependent arylalkylamine N-acetyltransferase. What is especially interesting, wMelCS genotype of Wolbachia increases stress resistance and the intensity of dopamine metabolism, whereas wMelPop strain decreases them. wMel, wMel2 and wMel4 genotypes of Wolbachia do not show any effect on the survival under heat stress or dopamine metabolism. L-DOPA treatment, known to increase the dopamine content in Drosophila, levels the difference in survival under heat stress between all studied groups.
conclusionsThe genotype of symbiont determines the effect that the symbiont has on the stress resistance of the host insect.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.