Evidence map›Paper›PMID 29299155›Full record

ArticleOncotarget2017

Neuroprotection by aripiprazole against β-amyloid-induced toxicity by P-CK2α activation via inhibition of GSK-3β.

So Youn Park, Hwa Kyoung Shin, Won Suk Lee, Sun Sik Bae, Koanhoi Kim, Ki Whan Hong, Chi Dae Kim

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Effects of Psychotropic Drugs on Ribosomal Genes and Protein Synthesis.International journal of molecular sciences · 2022
    Article
  4. Combination therapy with cilostazol, aripiprazole, and donepezil protects neuronal cells from β-amyloid neurotoxicity through synergistically enhanced SIRT1 expression.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2020
    Article
  5. Review
  6. Clinical trials of new drugs for Alzheimer disease.Journal of biomedical science · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

So Youn ParkDepartment of Pharmacology, School of Medicine, Pusan National University, Gyeongsangnam-do 50612, Republic of Korea.
Hwa Kyoung ShinDepartment of Korean Medical Science, School of Korean Medicine, Pusan National University, Gyeongsangnam-do 50612, Republic of Korea.
Won Suk LeeDepartment of Pharmacology, School of Medicine, Pusan National University, Gyeongsangnam-do 50612, Republic of Korea.
Sun Sik BaeDepartment of Pharmacology, School of Medicine, Pusan National University, Gyeongsangnam-do 50612, Republic of Korea.
Koanhoi KimDepartment of Pharmacology, School of Medicine, Pusan National University, Gyeongsangnam-do 50612, Republic of Korea.
Ki Whan HongGene & Cell Therapy Research Center for Vessel-associated Diseases, Pusan National University, Gyeongsangnam-do 50612, Republic of Korea.
Chi Dae KimDepartment of Pharmacology, School of Medicine, Pusan National University, Gyeongsangnam-do 50612, Republic of Korea.
Pusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychosis is reported over 30% of patients with Alzheimer's disease (AD) in clinics. Aripiprazole is an atypical antipsychotic drug with partial agonist activity at the D

Indexed as

alzheimer’s diseasearipiprazoleCK2αGSK-3βWnt/β-catenin pathway

Identifiers

PMID29299155
PMCPMC5746390
OpenAlexW2775157899

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.