Evidence map›Paper›PMID 29299405›Full record

ReviewTranslational lung cancer research2017

Clinical management of epidermal growth factor receptor mutation-positive non-small cell lung cancer patients after progression on previous epidermal growth factor receptor tyrosine kinase inhibitors: the necessity of repeated molecular analysis.

José Luís González-Larriba, Martín Lázaro-Quintela, Manuel Cobo, Manuel Dómine, Margarita Majem, Rosario García-Campelo

Open access · hybridAbstract readReview
In one paragraph

Review in Translational lung cancer research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

José Luís González-LarribaDepartment of Medical Oncology, San Carlos University Hospital, Madrid, Spain.
Martín Lázaro-QuintelaDepartment of Medical Oncology, Vigo University Hospital Complex, Vigo, Spain.
Manuel CoboDepartment of Medical Oncology, Málaga University Hospital, General and Virgen de la Victoria, IBIMA, Málaga, Spain.
Manuel DómineDepartment of Medical Oncology, Fundación Jiménez Díaz University Hospital, Madrid, Spain.
Margarita MajemDepartment of Medical Oncology, Santa Creu i Sant Pau University Hospital, Barcelona, Spain.
Rosario García-CampeloDepartment of Medical Oncology, A Coruña University Hospital, A Coruña, Spain.
Hospital Clínico San Carlos · ESHospital Clínico Universitario Virgen de la Victoria · ESHospital de Sant Pau · ESHospital Universitario Fundación Jiménez Díaz · ESUniversidade da Coruña · ESUniversity Hospital Complex Of Vigo · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the most important advances in the treatment of non-small cell lung cancer (NSCLC) has been the identification of molecular alterations vulnerable to targeted inhibition, such as mutations in the epidermal growth factor receptor (

Indexed as

Epidermal growth factor receptor (EGFR)liquid biopsyosimertinibrebiopsytyrosine kinase inhibitor (TKI)

Identifiers

PMID29299405
PMCPMC5750154
OpenAlexW2769481789

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.