Evidence map›Paper›PMID 29310617›Full record

Trial reportBMC pregnancy and childbirth2018

Exercise training during pregnancy reduces circulating insulin levels in overweight/obese women postpartum: secondary analysis of a randomised controlled trial (the ETIP trial).

Kirsti K Garnæs, Siv Mørkved, Kjell Å Salvesen, Øyvind Salvesen, Trine Moholdt

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC pregnancy and childbirth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01243554 (Exercise Training in Pregnancy. Good for the Mother - Good for the Child?), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01243554 nacompletednot on this map

Exercise Training in Pregnancy. Good for the Mother - Good for the Child?

TypeinterventionalSponsorNorwegian University of Science and TechnologyRan2010 to 2016Enrolled91ConditionsPregnancy, ObesityArmsExercise
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kirsti K GarnæsDepartment of Circulation and Medical Imaging, NTNU, Norwegian University of Science and Technology, Box 8905, 7491, Trondheim, Norway.
Siv MørkvedDepartment of Public Health and General Practice, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
Kjell Å SalvesenInstitute of clinical and molecular medicine, Norwegian University of Science and Tecnology, Trondheim, Norway.
Øyvind SalvesenDepartment of Public Health and General Practice, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
Trine MoholdtDepartment of Circulation and Medical Imaging, NTNU, Norwegian University of Science and Technology, Box 8905, 7491, Trondheim, Norway. trine.moholdt@ntnu.no.ORCID 0000-0003-1024-8088
Norwegian University of Science and Technology · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe primary aim was to investigate if supervised exercise training during pregnancy could reduce postpartum weight retention (PPWR) three months after delivery in overweight and obese women. We also measured circulating markers of cardiometabolic health, body composition, blood pressure, and physical activity level.

methodsThis was a secondary analysis of a randomised controlled trial in which 91 women with BMI ≥ 28 kg/m

resultsSeventy women participated three months after delivery, and PPWR was -0.8 kg in the exercise group (n = 36) and -1.6 in the control group (n = 34) (95% CI, -1.83, 3.84, p = 0.54). Women in the exercise group had significantly lower circulating insulin concentration; 106.3 pmol/l compared to the control group; 141.4 pmol/l (95% CI, -62.78, -7.15, p = 0.01), and showed a tendency towards lower homeostatic measurement of insulin resistance (HOMA2-IR) (3.5 vs. 5.0, 95% CI, -2.89, 0.01, p = 0.05). No women in the exercise group compared to three women in the control group were diagnosed with type 2 diabetes postpartum (p = 0.19). Of the women in the exercise group, 46.4% reported of exercising regularly, compared to 25.0% in the control group (p = 0.16).

conclusionsOffering supervised exercise training during pregnancy among overweight/obese women did not affect PPWR three months after delivery, but reduced circulating insulin levels. This was probably due to a higher proportion of women being active postpartum in the exercise group.

trial registrationClinicalTrials.gov ( NCT01243554 ), registration date: September 6, 2010.

Indexed as

AdultBlood GlucoseBody WeightDiabetes Mellitus, Type 2ExerciseFemaleHumansInsulinInsulin ResistanceObesityPostpartum PeriodPregnancyBlood GlucoseInsulinDiabetesHigh BMIMaternal risksPhysical activityPregnant

Identifiers

PMID29310617
PMCPMC5759335
OpenAlexW2782930237

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.