Evidence map›Paper›PMID 29311116›Full record

ArticleThe EMBO journal2018

STIM1 activation of adenylyl cyclase 6 connects Ca

Rajender K Motiani, Jyoti Tanwar, Desingu Ayyappa Raja, Ayushi Vashisht, Shivangi Khanna, Sachin Sharma, Sonali Srivastava, Sridhar Sivasubbu, Vivek T Natarajan, Rajesh S Gokhale

Open access · bronzeAbstract read
In one paragraph

Article in The EMBO journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 80 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Rajender K MotianiSystems Biology Group, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India rajmotiani@igib.in rsg@nii.ac.in.ORCID 0000-0002-8971-9008
Jyoti TanwarSystems Biology Group, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Desingu Ayyappa RajaSystems Biology Group, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Ayushi VashishtSystems Biology Group, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.ORCID 0000-0003-3458-5329
Shivangi KhannaSystems Biology Group, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Sachin SharmaSystems Biology Group, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Sonali SrivastavaSystems Biology Group, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Sridhar SivasubbuSystems Biology Group, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Vivek T NatarajanSystems Biology Group, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Rajesh S GokhaleSystems Biology Group, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India rajmotiani@igib.in rsg@nii.ac.in.ORCID 0000-0001-6597-2685
Institute of Genomics and Integrative Biology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoplasmic reticulum (ER)-plasma membrane (PM) junctions form functionally active microdomains that connect intracellular and extracellular environments. While the key role of these interfaces in maintenance of intracellular Ca

Indexed as

Adenylyl Cyclasesalpha-MSHAnimalsCalciumCalcium SignalingCell LineCell MembraneCell ProliferationCyclic AMPEndoplasmic ReticulumEnzyme ActivationGene Expression ProfilingMelanocytesMiceORAI1 ProteinSkin Pigmentationadenylyl cyclase 6Adenylyl Cyclasesalpha-MSHCalciumCyclic AMPORAI1 ProteinStromal Interaction Molecule 1ADCY6cAMPOrai1pigmentationSTIM1

Identifiers

PMID29311116
PMCPMC5830913
OpenAlexW2782804955

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.