Evidence map›Paper›PMID 29311357›Full record

ArticlePediatrics2018

Cardiovascular Risk Factors After Adolescent Bariatric Surgery.

Marc P Michalsky, Thomas H Inge, Todd M Jenkins, Changchun Xie, Anita Courcoulas, Michael Helmrath, Mary L Brandt, Carroll M Harmon, Mike Chen, John B Dixon and 2 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00474318 (Teen-Longitudinal Assessment of Bariatric Surgery), which is not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
14.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00474318 completednot on this map

Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Research Project

TypeobservationalSponsorAnn & Robert H Lurie Children's Hospital of ChicagoRan2007 to 2024Enrolled250ConditionsObesity
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 121 citations in OpenAlex.

  1. Pooled it
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  16. Long-Term Outcomes after Adolescent Bariatric Surgery.Journal of the American College of Surgeons · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 2 countries.

Marc P MichalskyNationwide Children's Hospital, The Ohio State University, Columbus, Ohio; marc.michalsky@nationwidechildrens.org.
Thomas H IngeUniversity of Colorado, Denver, Colorado and Children's Hospital Colorado, University of Colorado, Aurora, Colorado.
Todd M JenkinsCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Changchun XieUniversity of Cincinnati, Cincinnati, Ohio.
Anita CourcoulasUniversity of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Michael HelmrathCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Mary L BrandtTexas Children's Hospital, College of Medicine, Baylor University, Houston, Texas.
Carroll M HarmonWomen and Children's Hospital of Buffalo, Buffalo, New York.
Mike ChenUniversity of Alabama at Birmingham, Birmingham, Alabama.
John B DixonBaker Heart and Diabetes Institute, Melbourne, Victoria, Australia; and.
Elaine M UrbinaCincinnati Children's Hospital, University of Cincinnati, Cincinnati, Ohio.
Teen-LABS Consortium
Cincinnati Children's Hospital Medical Center · USBaker Heart and Diabetes Institute · AUChildren's Hospital Colorado · USTexas Children's Hospital · USThe Ohio State University · USUniversity of Alabama at Birmingham · USUniversity of Cincinnati · USUniversity of Pittsburgh Medical Center · USWomen & Children's Hospital of Buffalo · US

Funding

UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS · 1995 to 2026
$32.6M
ZOLENDRONIC ACID IN CHILDREN W/ SEVERE OSTEOGENESIS IMPERFECTAM01RR000188 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI DE LA GARZA, RICHARD · 1985 to 2011
$30.6M
University of Iowa Clinical and Translational Science Program (TL1)UL1RR025755 · NCRR · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2008 to 2011
$26.3M
Continuation of the Longitudinal Assessment of Bariatric Surgery (LABS) - DCCU01DK066557 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BELLE, STEVEN H. · 2003 to 2015
$15.8M
Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Research ProjectUM1DK072493 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI INGE, THOMAS HARRIS · 2011 to 2020
$10.5M
Cincinnati Center for Clinical and Translational Sciences and TrainingUL1TR000077 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., TSEVAT, JOEL · 2012 to 2014
$9.9M
UAB Center for Clinical and Translational Science (CCTS) UL1UL1TR000165 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2012 to 2013
$9.6M
Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) renewalUM1DK095710 · NIDDK · UNIVERSITY OF CINCINNATI · PI JENKINS, TODD M, XIE, CHANGCHUN · 2011 to 2020
$9.4M
Adolescent Bariatrics: Assessing Health Benefits & RisksU01DK072493 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI INGE, THOMAS HARRIS · 2006 to 2010
$8.7M
NCATS NIH HHS UL1 TR000005NCATS NIH HHS UL1 TR000077NCATS NIH HHS UL1 TR000165NCATS NIH HHS UL1 TR001425NCRR NIH HHS M01 RR000188NCRR NIH HHS UL1 RR024153NCRR NIH HHS UL1 RR025755NIDDK NIH HHS U01 DK066557NIDDK NIH HHS U01 DK072493NIDDK NIH HHS UM1 DK072493NIDDK NIH HHS UM1 DK095710
6 · The paper itself

Abstract

BACKGROUND AND

objectivesSeverely obese adolescents harbor numerous cardiovascular disease risk factors (CVD-RFs), which improve after metabolic and bariatric surgery (MBS). However, predictors of change in CVD-RFs among adolescents have not yet been reported.

methodsThe Teen-Longitudinal Assessment of Bariatric Surgery study (NCT00474318) prospectively collected anthropometric and health status data on 242 adolescents undergoing MBS at 5 centers. Predictors of change in CVD-RFs (blood pressure, lipids, glucose homeostasis, and inflammation) 3 years after Roux-en-Y gastric bypass and vertical sleeve gastrectomy were examined.

resultsThe mean (±SD) age of participants at baseline was 17 ± 1.6 years; 76% were girls, and 72% were white, with a median BMI of 51. Participants underwent Roux-en-Y gastric bypass (

conclusionsNumerous CVD-RFs improve among adolescents undergoing MBS. Increased weight loss, female sex, and younger age predict a higher probability of resolution of specific CVD-RFs. The elucidation of predictors of change in CVD-RFs may lead to refinements in patient selection and optimal timing of adolescent bariatric surgery designed to improve clinical outcomes.

Indexed as

Bariatric SurgeryAdolescentAge FactorsCardiovascular DiseasesC-Reactive ProteinFemaleGlycated HemoglobinHumansLipidsMaleObesity, MorbidPediatric ObesityRisk FactorsSex FactorsWeight LossYoung AdultC-Reactive ProteinGlycated Hemoglobinhemoglobin A1c protein, humanLipids

Identifiers

PMID29311357
PMCPMC5810605
OpenAlexW2782628573

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.