Evidence map›Paper›PMID 29323451›Full record

ReviewMicrocirculation (New York, N.Y. : 1994)2019

Microvascular involvement in systemic sclerosis and systemic lupus erythematosus.

Didem Saygin, Kristin B Highland, Adriano R Tonelli

Abstract readReview
In one paragraph

Review in Microcirculation (New York, N.Y. : 1994), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Microvascular markers in systemic sclerosis: a comparative OCT-angiography and nailfold videocapillaroscopy study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  8. Article
  9. Myocardial infarction in rheumatic diseases.Rheumatology international · 2025
    Review
  10. Observational
  11. Observational
  12. Correlation between cardiovascular magnetic resonance features and clinical characteristics of cardiac involvement in connective tissue diseases.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Quantitative evaluation of retinal and choroidal vascularity in systemic lupus erythematosus by SS-OCT/OCTA.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Didem SayginDepartment of Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.ORCID 0000-0003-1675-597X
Kristin B HighlandDepartment of Pulmonary, Allergy and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH, USA.
Adriano R TonelliDepartment of Pulmonary, Allergy and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH, USA.

Funding

Extrapulmonary Microvascular Dysfunction in Pulmonary Arterial HypertensionR01HL130307 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI TONELLI, ADRIANO · 2016 to 2020
$2.0M
NHLBI NIH HHS R01 HL130307
6 · The paper itself

Abstract

Microvascular changes play central roles in the pathophysiology of SSc and SLE, and represent major causes of morbidity and mortality in these patients. Therefore, clinical tools that can assess the microvasculature are of great importance both at the time of diagnosis and follow-up of these cases. These tools include capillaroscopy, laser imaging techniques, infrared thermography, and iontophoresis. In this review, we examined the clinical manifestations and pathobiology of microvascular involvement in SSc and SLE as well as the methodologies used to evaluate the microvasculature.

Indexed as

MicrocirculationMicroscopic AngioscopyCapillariesHumansLupus Erythematosus, SystemicScleroderma, Systemiccapillaroscopyiontophoresislasermicrovasculopathysclerodermasystemic lupus erythematosusvasculitis

Identifiers

PMID29323451
PMCPMC6041191

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.