Evidence map›Paper›PMID 29326697›Full record

ArticleFrontiers in immunology2017

Pacific Biosciences Sequencing and IMGT/HighV-QUEST Analysis of Full-Length Single Chain Fragment Variable from an

Audrey Hemadou, Véronique Giudicelli, Melissa Laird Smith, Marie-Paule Lefranc, Patrice Duroux, Sofia Kossida, Cheryl Heiner, N Lance Hepler, John Kuijpers, Alexis Groppi and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

  1. IMGTAntibodies (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. IMGTBiomolecules · 2022
    Article
  8. IMGTMethods in molecular biology (Clifton, N.J.) · 2022
    Article
  9. RNA metabolism and links to inflammatory regulation and disease.Cellular and molecular life sciences : CMLS · 2021
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Long-read amplicon denoising.Nucleic acids research · 2019
    Article
  15. Article
  16. IMGTAntibodies (Basel, Switzerland) · 2019
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Audrey HemadouCRMSB, UMR 5536, CNRS, Bordeaux, France.
Véronique GiudicelliIMGT®, The International ImMunoGeneTics Information System®, Laboratoire d'ImmunoGénétique Moléculaire, LIGM, Institut de Génétique Humaine, IGH, UMR 9002, CNRS, Montpellier University, Montpellier, France.
Melissa Laird SmithPacific Biosciences, Menlo Park, CA, United States.
Marie-Paule LefrancIMGT®, The International ImMunoGeneTics Information System®, Laboratoire d'ImmunoGénétique Moléculaire, LIGM, Institut de Génétique Humaine, IGH, UMR 9002, CNRS, Montpellier University, Montpellier, France.
Patrice DurouxIMGT®, The International ImMunoGeneTics Information System®, Laboratoire d'ImmunoGénétique Moléculaire, LIGM, Institut de Génétique Humaine, IGH, UMR 9002, CNRS, Montpellier University, Montpellier, France.
Sofia KossidaIMGT®, The International ImMunoGeneTics Information System®, Laboratoire d'ImmunoGénétique Moléculaire, LIGM, Institut de Génétique Humaine, IGH, UMR 9002, CNRS, Montpellier University, Montpellier, France.
Cheryl HeinerPacific Biosciences, Menlo Park, CA, United States.
N Lance HeplerPacific Biosciences, Menlo Park, CA, United States.
John KuijpersPacific Biosciences, Menlo Park, CA, United States.
Alexis GroppiUniversité de Bordeaux, Centre de Bioinformatique de Bordeaux (CBiB), Bordeaux, France.
Jonas KorlachPacific Biosciences, Menlo Park, CA, United States.
Philippe MondonLFB Biotechnologies, Lille, France.
Florence OttonesCRMSB, UMR 5536, CNRS, Bordeaux, France.
Marie-Josée Jacobin-ValatCRMSB, UMR 5536, CNRS, Bordeaux, France.
Jeanny Laroche-TraineauCRMSB, UMR 5536, CNRS, Bordeaux, France.
Gisèle Clofent-SanchezCRMSB, UMR 5536, CNRS, Bordeaux, France.
Centre National de la Recherche Scientifique · FRPacific Biosciences (United States) · USCentre de Résonance Magnétique des Systèmes Biologiques · FRUniversité de Montpellier · FRLFB (France) · FRUniversité de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phage-display selection of immunoglobulin (IG) or antibody single chain Fragment variable (scFv) from combinatorial libraries is widely used for identifying new antibodies for novel targets. Next-generation sequencing (NGS) has recently emerged as a new method for the high throughput characterization of IG and T cell receptor (TR) immune repertoires both

Indexed as

human antibodyIMGT/HighV-QUESTimmunoglobulinimmunoinformaticsnext-generation sequencingPacific Biosciences sequencingphage combinatorial librarysingle chain fragment variable

Identifiers

PMID29326697
PMCPMC5742356
OpenAlexW2779258318

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.