Evidence map›Paper›PMID 29339549›Full record

ArticleJournal of the American Society of Nephrology : JASN2018

Mona D Doshi, Mariella Ortigosa-Goggins, Amit X Garg, Lihua Li, Emilio D Poggio, Cheryl A Winkler, Jeffrey B Kopp

Registry-linked trialAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03615235 (APOL1 Long-term Kidney Transplantation Outcomes Network), which is not on this map. Cited by 76 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 2 pooled it
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03615235 active not recruitingnot on this mapstarted 2019, after this paper: background citation

APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

TypeobservationalSponsorWake Forest University Health SciencesRan2019 to 2027Enrolled5,000ConditionsKidney Diseases, Kidney Failure, Kidney Disease, Chronic
3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 2 syntheses or guidelines pooled it, 138 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Update on APOL1 and chronic kidney diseases in children.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  4. Donor medicine: An emerging field in nephrology.World journal of nephrology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Review
  12. Contextual factors of implementing APOL1 genetic testing into living kidney donor clinical evaluation.Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025
    Article
  13. Article
  14. Evaluating Risk in Kidney Living Donors.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Monogenic Kidney Diseases in Kidney Transplantation.Kidney international reports · 2024
    Review

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Mona D DoshiDivision of Nephrology, University of Michigan, Ann Arbor, Michigan; doshimd@med.umich.edu.
Mariella Ortigosa-GogginsDivision of Nephrology, Miami Transplant Institute, University of Miami, Miami, Florida.
Amit X GargDivision of Nephrology, Western University, London, Ontario, Canada.
Lihua LiDivision of Nephrology, Western University, London, Ontario, Canada.
Emilio D PoggioDepartment of Nephrology and Hypertension, Cleveland Clinic, Cleveland, Ohio; and.
Cheryl A WinklerBasic Research Laboratory, National Cancer Institute, Leidos Biomedical Research, Frederick Laboratory for Cancer Research, Frederick, Maryland and.
Jeffrey B KoppKidney Disease Branch of National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Western University · CACleveland Clinic · USLeidos Biomedical Research Inc. (United States)Miami Transplant Institute · USNational Institute of Diabetes and Digestive and Kidney Diseases · USUniversity of Michigan–Ann Arbor · US

Funding

Focal Segmental Glomerulosclerosis: Genetics & MechanismsZIADK043308 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI KOPP, JEFFREY BURNETT · 2009 to 2024
$15.7M
Genetics of Renal Disease in African AmericansZIABC010022 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WINKLER, CHERYL · 2009 to 2022
$8.9M
CIHR
6 · The paper itself

Abstract

Black living kidney donors are at higher risk of developing kidney disease than white donors. We examined the effect of the

Indexed as

Kidney TransplantationLiving DonorsAdultApolipoprotein L1Black PeopleDisease ProgressionFamilyFemaleFollow-Up StudiesGenetic Predisposition to DiseaseGenotypeGlomerular Filtration RateHumansHypertensionKidneyKidney Failure, ChronicAPOL1 protein, humanApolipoprotein L1human geneticskidney donationrenal function

Identifiers

PMID29339549
PMCPMC5875947
OpenAlexW2783484428

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.