Evidence map›Paper›PMID 29340679›Full record

Trial reportJAMA2018

Effect of Laparoscopic Sleeve Gastrectomy vs Laparoscopic Roux-en-Y Gastric Bypass on Weight Loss in Patients With Morbid Obesity: The SM-BOSS Randomized Clinical Trial.

Ralph Peterli, Bettina Karin Wölnerhanssen, Thomas Peters, Diana Vetter, Dino Kröll, Yves Borbély, Bernd Schultes, Christoph Beglinger, Jürgen Drewe, Marc Schiesser and 2 more

4 registry-linked trialsOpen access · greenAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in JAMA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 504 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
504citing papers in PubMed, 16 pooled it
129.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00356213 nacompletednot on this map

Laparoscopic Sleeve Gastrectomy or Laparoscopic Proximal Roux-Y-gastric Bypass in the Treatment of Morbid Obesity

TypeinterventionalSponsorUniversity Hospital, Basel, SwitzerlandRan2006 to 2017Enrolled217ConditionsMorbid ObesityArmssleeve gastrectomy, Roux-Y-gastric bypass
NCT03975478 naunknown statusnot on this mapstarted 2019, after this paper: background citation

BASALTO (Bariatric Surgery and LDL Cholesterol) Trial

TypeinterventionalSponsorParc de Salut MarRan2019 to 2023Enrolled36ConditionsBariatric SurgeryArmsGastric bypass, Sleeve gastrectomy
NCT04237857 unknown statusnot on this mapstarted 2020, after this paper: background citation

Long Term Incidence and Effect of Gastroesophageal Reflux Disease After Laparoscopic Sleeve Gastrectomy in Chinese Population

TypeobservationalSponsorChinese University of Hong KongRan2020 to 2025Enrolled100ConditionsGastroesophageal RefluxArmsLaparoscopic sleeve gastrectomy
NCT05330910 narecruitingnot on this mapstarted 2022, after this paper: background citation

A Randomized Controlled Trial Evaluating PAtients With Lax Gastroesophageal Junction to Initial Sleeve Gastrectomy With or Without Concomitant Crural Repair (REPAIR)

TypeinterventionalSponsorSengkang General HospitalRan2022 to 2028Enrolled96ConditionsObesity, Bariatric Surgery Candidate, Esophagus Injury, Gastroesophageal RefluxArmsLaparoscopic sleeve gastrectomy with concomitant hiatal hernia repair arm, Laparoscopic sleeve gastrectomy arm
3 · Its place in the literature

Who cites it

504 citing papers in PubMed, 16 syntheses or guidelines pooled it, 1,221 citations in OpenAlex.

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  5. Impact of bariatric surgery on gut microbiota in obese patients: A systematic review.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025
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444 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Ralph PeterliDepartment of Surgery, St Claraspital, Basel, Switzerland.
Bettina Karin WölnerhanssenDepartment of Clinical Research, St Claraspital, Basel, Switzerland.
Thomas PetersDepartment of Internal Medicine, St Claraspital, Basel, Switzerland.
Diana VetterDepartment of Visceral and Transplantation Surgery, University Hospital, Zürich, Switzerland.
Dino KröllDepartment of Surgery, University Hospital, Bern, Switzerland.
Yves BorbélyDepartment of Surgery, University Hospital, Bern, Switzerland.
Bernd SchultesSwiss Medical and Surgical Center, St Gallen, Switzerland.
Christoph BeglingerDepartment of Clinical Research, St Claraspital, Basel, Switzerland.
Jürgen DreweDepartment of Pharmacology and Toxicology, University Hospital, Basel, Switzerland.
Marc SchiesserDepartment of Surgery, Kantonsspital, St Gallen, Switzerland.
Philipp NettDepartment of Surgery, University Hospital, Bern, Switzerland.
Marco BueterDepartment of Visceral and Transplantation Surgery, University Hospital, Zürich, Switzerland.
St. Claraspital · CHUniversity Hospital of Bern · CHUniversity Hospital of Basel · CHUniversity Hospital of Zurich · CHKantonsspital St. Gallen · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Sleeve gastrectomy is increasingly used in the treatment of morbid obesity, but its long-term outcome vs the standard Roux-en-Y gastric bypass procedure is unknown. Objective: To determine whether there are differences between sleeve gastrectomy and Roux-en-Y gastric bypass in terms of weight loss, changes in comorbidities, increase in quality of life, and adverse events. Design, Setting, and Participants: The Swiss Multicenter Bypass or Sleeve Study (SM-BOSS), a 2-group randomized trial, was conducted from January 2007 until November 2011 (last follow-up in March 2017). Of 3971 morbidly obese patients evaluated for bariatric surgery at 4 Swiss bariatric centers, 217 patients were enrolled and randomly assigned to sleeve gastrectomy or Roux-en-Y gastric bypass with a 5-year follow-up period. Interventions: Patients were randomly assigned to undergo laparoscopic sleeve gastrectomy (n = 107) or laparoscopic Roux-en-Y gastric bypass (n = 110). Main Outcomes and Measures: The primary end point was weight loss, expressed as percentage excess body mass index (BMI) loss. Exploratory end points were changes in comorbidities and adverse events. Results: Among the 217 patients (mean age, 45.5 years; 72% women; mean BMI, 43.9) 205 (94.5%) completed the trial. Excess BMI loss was not significantly different at 5 years: for sleeve gastrectomy, 61.1%, vs Roux-en-Y gastric bypass, 68.3% (absolute difference, -7.18%; 95% CI, -14.30% to -0.06%; P = .22 after adjustment for multiple comparisons). Gastric reflux remission was observed more frequently after Roux-en-Y gastric bypass (60.4%) than after sleeve gastrectomy (25.0%). Gastric reflux worsened (more symptoms or increase in therapy) more often after sleeve gastrectomy (31.8%) than after Roux-en-Y gastric bypass (6.3%). The number of patients with reoperations or interventions was 16/101 (15.8%) after sleeve gastrectomy and 23/104 (22.1%) after Roux-en-Y gastric bypass. Conclusions and Relevance: Among patients with morbid obesity, there was no significant difference in excess BMI loss between laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass at 5 years of follow-up after surgery. Trial Registration: clinicaltrials.gov Identifier: NCT00356213.

Indexed as

GastrectomyGastric BypassLaparoscopyWeight LossAdultBody Mass IndexFemaleFollow-Up StudiesGastroesophageal RefluxHumansMaleMiddle AgedObesity, MorbidPostoperative ComplicationsQuality of Life

Identifiers

PMID29340679
PMCPMC5833546
OpenAlexW2783324876

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.