Evidence map›Paper›PMID 29342865›Full record

Trial reportNutrients2018

Acute Post-Prandial Cognitive Effects of Brown Seaweed Extract in Humans.

Crystal F Haskell-Ramsay, Philippa A Jackson, Fiona L Dodd, Joanne S Forster, Jocelyn Bérubé, Carey Levinton, David O Kennedy

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
  6. Review
  7. Review
  8. Phenolics as GABAMolecules (Basel, Switzerland) · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Crystal F Haskell-RamsayBrain, Performance and Nutrition Research Centre, Northumbria University, Newcastle Upon-Tyne NE1 8ST, UK. crystal.haskell-ramsay@northumbria.ac.uk.ORCID 0000-0001-8153-0895
Philippa A JacksonBrain, Performance and Nutrition Research Centre, Northumbria University, Newcastle Upon-Tyne NE1 8ST, UK. philippa.jackson@northumbria.ac.uk.ORCID 0000-0002-9492-134X
Fiona L DoddBrain, Performance and Nutrition Research Centre, Northumbria University, Newcastle Upon-Tyne NE1 8ST, UK. f.dodd@northumbria.ac.uk.
Joanne S ForsterBrain, Performance and Nutrition Research Centre, Northumbria University, Newcastle Upon-Tyne NE1 8ST, UK. jo.forster@northumbria.ac.uk.
Jocelyn BérubéinnoVactiv Inc., Rimouski, QC G5L 9H3, Canada. jberube@innovactiv.com.
Carey LevintonInstitute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON M4G 4J6, Canada. carey.levinton@utoronto.ca.
David O KennedyBrain, Performance and Nutrition Research Centre, Northumbria University, Newcastle Upon-Tyne NE1 8ST, UK. david.kennedy@northumbria.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(Poly)phenols and, specifically, phlorotannins present in brown seaweeds have previously been shown to inhibit α-amylase and α-glucosidase, key enzymes involved in the breakdown and intestinal absorption of carbohydrates. Related to this are observations of modulation of post-prandial glycemic response in mice and increased insulin sensitivity in humans when supplemented with seaweed extract. However, no studies to date have explored the effect of seaweed extract on cognition. The current randomized, placebo-controlled, double-blind, parallel groups study examined the impact of a brown seaweed extract on cognitive function post-prandially in 60 healthy adults (

Indexed as

Postprandial PeriodAdolescentAdultAgedalpha-Amylasesalpha-GlucosidasesBlood GlucoseCognitionDouble-Blind MethodFemaleHumansInsulinInsulin ResistanceMaleMiddle AgedPolyphenolsalpha-Amylasesalpha-GlucosidasesBlood GlucoseInsulinPolyphenolscognitioncognitivemoodphenolicphlorotanninphytochemicalpolyphenolseaweed

Identifiers

PMID29342865
PMCPMC5793313

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.