Evidence map›Paper›PMID 29346256›Full record

ArticleTransplantation2018

Causes, Preventability, and Cost of Unplanned Rehospitalizations Within 30 Days of Discharge After Lung Transplantation.

Andrew M Courtwright, Derek Zaleski, Lisa Gardo, Vivek N Ahya, Jason D Christie, Maria Crespo, Denis Hadjiliadis, James Lee, Maria Molina, Namrata Patel and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in Transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04184180 (Effects of an Inpatient Pulmonary Rehabilitation Programme on Frailty in Patients After Lung-Transplantation), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04184180 completednot on this mapstarted 2019, after this paper: background citation

Effects of an Inpatient Pulmonary Rehabilitation Programme on Frailty in Patients After Lung-Transplantation

TypeobservationalSponsorKlaus KennRan2019 to 2020Enrolled33ConditionsAdvanced Lung Disease, COPD, Interstitial Lung Disease
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Frailty in lung transplant recipients is associated with anemia and telomere dysfunction but independent of epigenetic age.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Cellular Senescence and Frailty in Transplantation.Current transplantation reports · 2023
    Article
  11. Old Age and Frailty in Deceased Organ Transplantation and Allocation-A Plea for Geriatric Assessment and Prehabilitation.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
  12. Place-based heterogeneity in lung transplant recipient outcomes.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  13. Article
  14. Article
  15. Article
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  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Andrew M CourtwrightPulmonary and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA.
Derek ZaleskiGood Shepard Penn Partners, Philadelphia, PA.
Lisa GardoPulmonary and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA.
Vivek N AhyaPulmonary and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA.
Jason D ChristiePulmonary and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA.
Maria CrespoPulmonary and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA.
Denis HadjiliadisPulmonary and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA.
James LeePulmonary and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA.
Maria MolinaCardiothoracic Surgery, University of Pennsylvania, Philadelphia, PA.
Namrata PatelPulmonary and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA.
Mary PorteousPulmonary and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA.
Edward E CantuCardiothoracic Surgery, University of Pennsylvania, Philadelphia, PA.
Christian BermudezCardiothoracic Surgery, University of Pennsylvania, Philadelphia, PA.
Joshua M DiamondPulmonary and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA.

Funding

RESPIRATORY RESEARCHT32HL007633 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI George R Washko · 1985 to 2026
$14.9M
Mentored Patient Oriented Research in Lung TransplantationK24HL115354 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIE, JASON D · 2012 to 2021
$1.2M
Lung Transplant donor: prediction, evaluation, and mechanismK23HL116656 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CANTU, EDWARD · 2013 to 2017
$872k
Long Pentraxin-3 genomics and outcomes after lung transplantationK23HL121406 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI DIAMOND, JOSHUA M. · 2014 to 2017
$629k
Advanced diagnostics for donor lung assessment and ex vivo lung perfusion candidate selectionR03HL135227 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CANTU, EDWARD · 2016 to 2017
$161k
NHLBI NIH HHS K23 HL116656NHLBI NIH HHS K23 HL121406NHLBI NIH HHS K24 HL115354NHLBI NIH HHS R03 HL135227NHLBI NIH HHS T32 HL007633
6 · The paper itself

Abstract

backgroundUnplanned rehospitalizations (UR) within 30 days of discharge are common after lung transplantation. It is unknown whether UR represents preventable gaps in care or necessary interventions for complex patients. The objective of this study was to assess the incidence, causes, risk factors, and preventability of UR after initial discharge after lung transplantation.

methodsThis was a single-center prospective cohort study. Subjects completed a modified short physical performance battery to assess frailty at listing and at initial hospital discharge after transplantation and the State-Trait Anxiety Inventory at discharge. For each UR, a study staff member and the patient's admitting or attending clinician used an ordinal scale (0, not; 1, possibly; 2, definitely preventable) to rate readmission preventability. A total sum score of 2 or higher defined a preventable UR.

resultsOf the 90 enrolled patients, 30 (33.3%) had an UR. The single most common reasons were infection (7 [23.3%]) and atrial tachyarrhythmia (5 [16.7%]). Among the 30 URs, 9 (30.0%) were deemed preventable. Unplanned rehospitalization that happened before day 30 were more likely to be considered preventable than those between days 30 and 90 (30.0% versus 6.2%, P = 0.04). Discharge frailty, defined as short physical performance battery less than 6, was the only variable associated with UR on multivariable analysis (odds ratio, 3.4; 95% confidence interval, 1.1-11.8; P = 0.04).

conclusionsAlthough clinicians do not rate the majority of UR after lung transplant as preventable, discharge frailty is associated with UR. Further research should identify whether modification of discharge frailty can reduce UR.

Indexed as

Hospital CostsPatient DischargeAdultAgedAnxietyFemaleFrailtyHealth StatusHumansIncidenceLung TransplantationMaleMiddle AgedPatient ReadmissionPhiladelphiaPostoperative Complications

Identifiers

PMID29346256
PMCPMC5924417

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.