ArticleJAMA cardiology2018
Association of Resting Heart Rate and Temporal Changes in Heart Rate With Outcomes in Participants of the Atherosclerosis Risk in Communities Study.
Article in JAMA cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 57 citations in OpenAlex.
- Effects of exergaming versus endurance training on cardiorespiratory fitness and hemodynamic parameters: a randomized controlled trial.European journal of applied physiology · 2025Trial
- A Pilot Randomized Controlled Trial Using SystemCHANGE™ Approach to Increase Physical Activity in Older Kidney Transplant Recipients.Progress in transplantation (Aliso Viejo, Calif.) · 2020Trial
- Association Between Adherence To The French Dietary Guidelines And Lower Resting Heart Rate, Longer Diastole Duration, And Lower Myocardial Oxygen Consumption. The NUTRIVASC Study.Vascular health and risk management · 2019Trial
- Article
- Joint Modeling of Fasting Blood Sugar Changes and Cardiovascular Disease Progression in Type-2 Diabetes Mellitus Patients: A Retrospective Cohort Study.Health science reports · 2026Article
- Sex-specific longitudinal changes in resting heart rate and all-cause heart failure: insights from the HUNT study.Frontiers in cardiovascular medicine · 2026Article
- Association between long-term visit-to-visit resting heart rate variability and cognitive decline: evidence from two national cohorts.BMC psychiatry · 2025Article
- A guide to consumer-grade wearables in cardiovascular clinical care and population health for non-experts.NPJ cardiovascular health · 2025Review
- The utility of personal wearable data in long COVID and personalized patient care.NPJ digital medicine · 2024Article
- Resting Heart Rate and Incident Atrial Fibrillation in Black Adults in the Jackson Heart Study.JAMA network open · 2024Article
- Temporal Changes in Resting Heart Rate and Risk of Diabetes Mellitus.Diabetes & metabolism journal · 2024Article
- Time-variant associations of ambulatory pulse rate with short-term neurologic functional outcomes following acute ischemic stroke.Journal of human hypertension · 2023Article
- Dynamic changes in nocturnal heart rate predict short-term cardiovascular events in patients using the wearable cardioverter-defibrillator: from the WEARIT-France cohort study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- ANMCO-SIMEU consensus document: appropriate management of atrial fibrillation in the emergency department.European heart journal supplements : journal of the European Society of Cardiology · 2023Article
- Prediction of SYNTAX score II improvement by adding temporal heart rate changes between discharge and first outpatient visit in patients with acute myocardial infarction.BMC cardiovascular disorders · 2022Article
- Sinus Tachycardia: a Multidisciplinary Expert Focused Review.Circulation. Arrhythmia and electrophysiology · 2022Review
- Unexpected pulmonary edema and cardiac arrest following wedge resection of spontaneous pneumothorax -A case report.Anesthesia and pain medicine · 2022Article
- Association Between Temporal Changes in Early Repolarization Pattern With Long-Term Cardiovascular Outcome: A Population-Based Cohort Study.Journal of the American Heart Association · 2022Article
- Estrogen Metabolite 2-Methoxyestradiol Attenuates Blood Pressure in Hypertensive Rats by Downregulating Angiotensin Type 1 Receptor.Frontiers in physiology · 2022Article
- Diet quality trajectories and cardiovascular phenotypes/metabolic syndrome risk by 11-12 years.International journal of obesity (2005) · 2021Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
Abstract
Importance: Time-updated heart rate (HR) and temporal change in HR (ΔHR) are associated with outcome in individuals with established heart failure (HF). Whether these factors are associated with outcomes in a community-based cohort is unclear. Objective: To determine whether the time-updated analysis of resting HR, defined as the most recent HR value measured before occurrence of an event or the end of study, and ΔHR over time are associated with outcomes in a community-based cohort. Design, Setting, and Participants: A total of 15 680 participants were enrolled in the Atherosclerosis Risk in Communities cohort study, with HR recorded at baseline and during 3 follow-up visits from 1987 to 1998, with a median interval between visits of 3.0 (interquartile range, 2.9-4.0) years. The ΔHR was calculated by assessing a change in HR from the preceding visit. Participants were followed up until December 31, 2014, equating to 28 years of follow-up. The present study was conducted from March 2014 to June 2016 with updated analysis. Main Outcomes and Measures: Baseline HR, time-updated HR, and ΔHR associated with outcomes, adjusted for established baseline and time-updated risk factors and medications. The main outcomes measures included all-cause mortality, incident HF, incident myocardial infarction, stroke, and cardiovascular and noncardiovascular death. Results: Of the 15 680 participants, 8656 (55.2%) were women, mean (SD) age was 54 (6) years, and 4218 (26.9%) were African American. Time-updated HR and ΔHR were associated with death, incident HF, incident myocardial infarction, stroke, and cardiovascular and noncardiovascular death compared with baseline HR. For example, a ΔHR from the preceding visit was significantly associated with increased risk of all-cause mortality (adjusted hazard ratio, 1.12; 95% CI, 1.10-1.15; P < .001 for every 5-bpm increase in HR from the preceding visit) and time-updated HR was also significantly associated with increased risk of all-cause mortality (adjusted hazard ratio, 1.14; 95% CI, 1.12-1.17; P < .001 for every 5-bpm higher time-updated HR). Conclusions and Relevance: In a community-based cohort, time-updated HR and ΔHR are associated with mortality and nonfatal outcomes of incident HF, myocardial infarction, and stroke.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.