Trial reportJournal of acquired immune deficiency syndromes (1999)2018
Randomized Controlled Trial of the SystemCHANGE Intervention on Behaviors Related to Cardiovascular Risk in HIV+ Adults.
Trial report in Journal of acquired immune deficiency syndromes (1999), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Components in downstream health promotions to reduce sugar intake among adults: a systematic review.Nutrition journal · 2024Pooled it
- Effects of Physical Activity Interventions on Health Outcomes among Older Adults Living with HIV: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Use of the Healthy Eating Index in Intervention Studies for Cardiometabolic Risk Conditions: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2021Pooled it
- Assessing Mediation and Moderation of an Efficacious Physical Activity Intervention for African American Men Living with HIV: The Influence of Self-Efficacy in Behavior Change.AIDS and behavior · 2026Trial
- Effects of a Health Promotion Intervention on Physical Activity in African American Men Living with HIV: Randomized Controlled Trial.AIDS patient care and STDs · 2021Trial
- Trial
- The Effect of an HIV Self-Management Intervention on Neurocognitive Behavioral Processing.Western journal of nursing research · 2019Trial
- Higher steps per day and better diet quality associated with lower symptom burden in adults with HIV: results from the PROSPER-HIV study.Research connections · 2026Article
- Wearable device monitoring of HIV health in the face of climate change and weather exposures: protocol for a mixed-methods study.BMJ open · 2025Article
- Efficacy of Health Promotion Interventions Aimed to Improve Health Gains in Middle-Aged Adults-A Systematic Review.Geriatrics (Basel, Switzerland) · 2023Review
- The Role of the Social Determinants of Health on Engagement in Physical Activity or Exercise among Adults Living with HIV: A Scoping Review.International journal of environmental research and public health · 2022Article
- Working status and seasonal meteorological conditions predict physical activity levels in people living with HIV.AIDS care · 2022Article
- Metabolic Changes in Pediatric HIV-Positive Patients and Potential Lifestyle Interventional Strategies.Cureus · 2021Review
- Self-management: A comprehensive approach to improve quality of life among people living with HIV in Indonesia.Belitung nursing journal · 2021Article
- Body Composition Changes in Response to Moderate- or High-Intensity Exercise Among Older Adults With or Without HIV Infection.Journal of acquired immune deficiency syndromes (1999) · 2020Article
- The relationship of cardiorespiratory function, fatigue and depressive symptoms in PLHIV.AIDS care · 2020Article
- Obesity and Weight Gain in Persons with HIV.Current HIV/AIDS reports · 2020 · on this mapReview
- Behavioral Weight Loss: A Promising Treatment for Obesity in Adults with HIV.AIDS and behavior · 2020Review
- Impact of Genetic and Nongenetic Factors on Body Mass Index and Waist-Hip Ratio Change in HIV-Infected Individuals Initiating Antiretroviral Therapy.Open forum infectious diseases · 2020Article
- Contemporary Lifestyle Modification Interventions to Improve Metabolic Comorbidities in HIV.Current HIV/AIDS reports · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo examine the effect of a lifestyle behavior intervention (SystemCHANGE) on physical activity and diet quality among sedentary people living with HIV (PLHIV). All participants expressed a desire to improve lifestyle health behaviors.
methodsOne hundred and seven HIV+ adults were randomized to either the intervention (6, in-person, standardized group sessions focusing on improving lifestyle behaviors) or a control condition (general advice on AHA diet and exercise guidelines). All participants wore an ActiGraph accelerometer and completed 24-hour dietary recalls at baseline, 3, and 6 months. Generalized estimating equations were used to examine intervention effects. The primary activity outcome was time spent in moderate-to-vigorous physical activity, and the primary dietary outcome was Healthy Eating Index.
resultsMean age was 53 years, 65% were male, and 86% African American. Approximately 90% attended at least half of the sessions and 60% attended 5 or more sessions. The intervention did not significantly improve our primary lifestyle behavior endpoints (P ≥ 0.05); however, intervention participants consumed fewer carbohydrates-primarily sugar-sweetened beverages-per day and lost 0.732 kg body weight compared with a 0.153 weight gain in the control group (P = 0.03).
conclusionsAmong sedentary PLHIV at high risk of cardiovascular disease, the SystemCHANGE intervention reduced daily carbohydrate intake and body weight, but did not increase physical activity or improve overall diet quality. Future work should identify fundamental personal, interpersonal, and contextual factors that will increase physical activity and improve overall diet quality among this population, and integrate these factors into tailored, lifestyle interventions for aging PLHIV.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.