Evidence map›Paper›PMID 29374074›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

CD22 Promotes B-1b Cell Responses to T Cell-Independent Type 2 Antigens.

Karen M Haas, Kristen L Johnson, James P Phipps, Cardinal Do

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Noncanonical B Cells: Characteristics of Uncharacteristic B Cells.Journal of immunology (Baltimore, Md. : 1950) · 2023
    Review
  6. Enhanced IgGImmunity, inflammation and disease · 2021
    Article
  7. Review
  8. B Cell Subsets Differentially Contribute to the T Cell-Independent Memory Pool.Journal of immunology (Baltimore, Md. : 1950) · 2020
    Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Karen M HaasDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27157 kmhaas@wakehealth.edu.
Kristen L JohnsonDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27157.
James P PhippsDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27157.
Cardinal DoDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27157.ORCID 0000-0002-7705-6059
Wake Forest University · US

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
Regulation of Memory B Cell Responses to Polysaccharide AntigensR01AI118876 · NIAID · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HAAS, KAREN M · 2015 to 2019
$1.9M
REGULATION OF PROTECTIVE HUMORAL IMMUNITY TO STREPTOCOCCUS PNEUMONIAE BY PD-1R21AI095800 · NIAID · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HAAS, KAREN M · 2011 to 2012
$407k
NCI NIH HHS P30 CA012197NIAID NIH HHS R01 AI118876NIAID NIH HHS R21 AI095800
6 · The paper itself

Abstract

CD22 (Siglec-2) is a critical regulator of B cell activation and survival. CD22

Indexed as

AnimalsAntigens, CD19Antigens, T-IndependentB-LymphocytesCell DifferentiationCell ProliferationLymphocyte ActivationMiceMice, Inbred C57BLReceptors, Antigen, B-CellSialic Acid Binding Ig-like Lectin 2Signal TransductionT-LymphocytesAntigens, CD19Antigens, T-IndependentCd22 protein, mouseReceptors, Antigen, B-CellSialic Acid Binding Ig-like Lectin 2

Identifiers

PMID29374074
PMCPMC5821584
OpenAlexW2784537537

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.